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Arachidonate 15-Lipoxygenase MeSH Descriptor Data 2024


MeSH Heading
Arachidonate 15-Lipoxygenase
Tree Number(s)
D08.811.682.690.416.583.500.065
D12.776.556.579.374.568.500.030
Unique ID
D001093
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D001093
Scope Note
An enzyme that catalyzes the oxidation of arachidonic acid to yield 15-hydroperoxyarachidonate (15-HPETE) which is rapidly converted to 15-hydroxy-5,8,11,13-eicosatetraenoate (15-HETE). The 15-hydroperoxides are preferentially formed in NEUTROPHILS and LYMPHOCYTES.
Entry Term(s)
15-Lipoxygenase
Arachidonic Acid 15-Lipoxygenase
Registry Numbers
EC 1.13.11.33
CAS Type 1 Name
Arachidonate:oxygen 15-oxidoreductase
Previous Indexing
Lipoxygenases (1974-1986)
Oxygenases (1966-1973)
Public MeSH Note
91; was see under ARACHIDONATE LIPOXYGENASES 1987-90
History Note
91(87); was see under ARACHIDONATE LIPOXYGENASES 1987-90
Entry Combination
antagonists & inhibitors:Lipoxygenase Inhibitors
Date Established
1991/01/01
Date of Entry
1986/06/16
Revision Date
2010/06/25
Arachidonate 15-Lipoxygenase Preferred
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