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Arachidonate 15-Lipoxygenase MeSH Descriptor Data 2026
An enzyme that catalyzes the oxidation of arachidonic acid to yield 15-hydroperoxyarachidonate (15-HPETE) which is rapidly converted to 15-hydroxy-5,8,11,13-eicosatetraenoate (15-HETE). The 15-hydroperoxides are preferentially formed in NEUTROPHILS and LYMPHOCYTES.
Entry Term(s)
15-Lipoxygenase
Arachidonic Acid 15-Lipoxygenase
Registry Numbers
EC 1.13.11.33
CAS Type 1 Name
Arachidonate:oxygen 15-oxidoreductase
Previous Indexing
Lipoxygenases (1974-1986)
Oxygenases (1966-1973)
Public MeSH Note
91; was see under ARACHIDONATE LIPOXYGENASES 1987-90
History Note
91(87); was see under ARACHIDONATE LIPOXYGENASES 1987-90
An enzyme that catalyzes the oxidation of arachidonic acid to yield 15-hydroperoxyarachidonate (15-HPETE) which is rapidly converted to 15-hydroxy-5,8,11,13-eicosatetraenoate (15-HETE). The 15-hydroperoxides are preferentially formed in NEUTROPHILS and LYMPHOCYTES.