MeSH Browser

MeSH Heading: Colistin
Tree Number(s): D04.345.566.780.110; D10.477.750.110; D12.644.050.600.110; D12.644.066.500.600.110; D12.644.641.780.110; D12.776.543.695.054.600.110
Unique ID: D003091
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D003091
Scope Note: Cyclic polypeptide antibiotic from Bacillus colistinus. It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally.
Entry Term(s): Colimycin; Colisticin; Colistin Sulfate; Coly-Mycin; Polymyxin E; Totazina
Pharm Action: Anti-Bacterial Agents
Registry Number: Z67X93HJG1
Related Numbers: 1066-17-7; WP15DXU577
CAS Type 1 Name: Colistin
NLM Classification #: QV 350
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2021/05/10

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0004767
Registry Number: Z67X93HJG1
Related Numbers: 1066-17-7; WP15DXU577
Scope Note: Cyclic polypeptide antibiotic from Bacillus colistinus. It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally.
Terms: Colistin Preferred Term
Term UI T008969
Date01/01/1999
LexicalTag NON
ThesaurusID; Polymyxin E
Term UI T008971
Date03/30/1977
LexicalTag NON
ThesaurusID UNK (19XX); Colimycin
Term UI T008967
Date09/20/1984
LexicalTag NON
ThesaurusID UNK (19XX); Colisticin
Term UI T008968
Date11/22/1989
LexicalTag NON
ThesaurusID NLM (1990)

Colistin MeSH Descriptor Data 2023