A mixture of polymyxins B1 and B2, obtained from BACILLUS POLYMYXA strains. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes. Polymyxin B is used for treatment of infections with gram-negative bacteria, but may be neurotoxic and nephrotoxic.
1991; was see under POLYMYXINS 1978-90; was AEROSPORIN see under POLYMYXIN 1971-77, see POLYMYXIN 1963-70; AEROSPORIN was see POLYMYXIN B 1978-93
Online Note
use POLYMYXIN B to search AEROSPORIN 1975-93; use POLYMYXINS 1966-74
History Note
1991(1978); was see under POLYMYXINS 1978-90; was AEROSPORIN see under POLYMYXIN 1971-77, see POLYMYXIN 1963-70; AEROSPORIN was see POLYMYXIN B 1978-93
A mixture of polymyxins B1 and B2, obtained from BACILLUS POLYMYXA strains. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes. Polymyxin B is used for treatment of infections with gram-negative bacteria, but may be neurotoxic and nephrotoxic.
