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Desipramine MeSH Descriptor Data 2021


MeSH Heading
Desipramine
Tree Number(s)
D03.633.300.240.281
Unique ID
D003891
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D003891
Scope Note
A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
Entry Term(s)
Apo-Desipramine
Demethylimipramine
Desipramine Hydrochloride
Desmethylimipramine
Norpramin
Novo-Desipramine
Nu-Desipramine
PMS-Desipramine
Pertofran
Pertofrane
Pertrofran
Petylyl
Ratio-Desipramine
Pharm Action
Antidepressive Agents, Tricyclic
Enzyme Inhibitors
Adrenergic Uptake Inhibitors
Registry Number
TG537D343B
Related Numbers
1Y58DO4MY1
50-47-5
58-28-6
CAS Type 1 Name
5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N-methyl-
NLM Classification #
QV 77.5
Public MeSH Note
65
History Note
65(63)
Date Established
1965/01/01
Date of Entry
1999/01/01
Revision Date
2017/05/24
Desipramine Preferred
Desipramine Hydrochloride Narrower
Norpramin Narrower
Ratio-Desipramine Narrower
Nu-Desipramine Narrower
Pertofrane Narrower
Petylyl Narrower
PMS-Desipramine Narrower
Apo-Desipramine Narrower
Novo-Desipramine Narrower
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