MeSH Browser

MeSH Heading: Digoxin
Tree Number(s): D04.210.500.155.580.130.500.436; D04.210.500.155.580.130.688; D09.408.180.261.436
Unique ID: D004077
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D004077
Annotation: do not confuse with DIGITOXIN
Scope Note: A cardiotonic glycoside obtained mainly from Digitalis lanata; it consists of three sugars and the aglycone DIGOXIGENIN. Digoxin has positive inotropic and negative chronotropic activity. It is used to control ventricular rate in ATRIAL FIBRILLATION and in the management of congestive heart failure with atrial fibrillation. Its use in congestive heart failure and sinus rhythm is less certain. The margin between toxic and therapeutic doses is small. (From Martindale, The Extra Pharmacopoeia, 30th ed, p666)
Entry Term(s): Digacin; Digitek; Digoregen; Digoxina Boehringer; Digoxine Nativelle; Dilanacin; Hemigoxine Nativelle; Lanacordin; Lanicor; Lanoxicaps; Lanoxin; Lanoxin-PG; Lenoxin; Mapluxin
Pharm Action: Anti-Arrhythmia Agents
Cardiotonic Agents
Enzyme Inhibitors
Registry Number: 73K4184T59
Related Numbers: 20830-75-5
CAS Type 1 Name: Card-20(22)-enolide, 3-((O-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1-4)-O-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1-4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl)oxy)-12,14-dihydroxy-, (3beta,5beta,12beta)-
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2017/05/24

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Digoxin MeSH Descriptor Data 2023