MeSH Browser

MeSH Heading: Dihydroxyphenylalanine
Tree Number(s): D02.092.311.200; D02.455.426.559.389.657.166.175.200; D12.125.072.050.685.400; D12.125.072.050.875.130
Unique ID: D004295
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D004295
Annotation: check text to see if LEVODOPA; (L-DOPA); is not meant instead
Scope Note: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
Entry Term(s): 3,4-Dihydroxyphenylalanine; 3-Hydroxy-DL-tyrosine; Dihydroxyphenylalanine Hydrochloride, (2:1); Dopa; beta-Hydroxytyrosine
Pharm Action: Dopamine Agents
Registry Number: 63-84-3
Related Numbers: 37466-26-5
CAS Type 1 Name: DL-Tyrosine, 3-hydroxy-
NLM Classification #: WK 725
See Also: Dopa Decarboxylase; Dopamine
Public MeSH Note: 2002; see DOPA 1966-2001
History Note: 2002(1966); for BETA-HYDROXYTYROSINE use DIHYDOXYPHENYLALANINE (NM) 1989-1991
Date Established: 2002/01/01
Date of Entry: 1999/01/01
Revision Date: 2018/06/30

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0006754
Registry Number: 63-84-3
Related Numbers: 37466-26-5
Scope Note: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
Terms: Dihydroxyphenylalanine Preferred Term
Term UI T013132
Date12/26/1974
LexicalTag NON
ThesaurusID UNK (19XX); beta-Hydroxytyrosine
Term UI T013135
Date07/31/1991
LexicalTag NON
ThesaurusID NLM (1992); 3-Hydroxy-DL-tyrosine
Term UI T013134
Date07/31/1991
LexicalTag NON
ThesaurusID NLM (1992); 3,4-Dihydroxyphenylalanine
Term UI T013131
Date07/31/1991
LexicalTag NON
ThesaurusID NLM (1992); Dopa
Term UI T013133
Date01/01/1999
LexicalTag ACR
ThesaurusID NLM (1966)

Dihydroxyphenylalanine MeSH Descriptor Data 2023