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Fenclonine MeSH Descriptor Data 2022


MeSH Heading
Fenclonine
Tree Number(s)
D12.125.072.050.685.440
Unique ID
D010134
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D010134
Scope Note
A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin.
Entry Term(s)
CP-10,188
DL-3-(4-Chlorophenyl)alanine
Fenclonin
Fenclonine (L)-Isomer
Fenclonine Hydrobromide
Fenclonine Hydrochloride
Fenclonine, (D)-Isomer
p-Chlorophenylalanine
para-Chlorophenylalanine
Pharm Action
Enzyme Inhibitors
Serotonin Antagonists
Registry Number
R5J7E3L9SP
Related Numbers
14091-08-8
14173-39-8
1991-78-2
23633-07-0
51274-82-9
55327-86-1
7424-00-2
CAS Type 1 Name
DL-Phenylalanine, 4-chloro-
Previous Indexing
Phenylalanine (1966-1970)
Public MeSH Note
93; see P-CHLOROPHENYLALANINE 1973-92; for FENCLONINE see P-CHLOROPHENYLALANINE 1978-92
History Note
93(71)
Date Established
1973/01/01
Date of Entry
1999/01/01
Revision Date
2013/07/08
Fenclonine Preferred
Fenclonine, (D)-Isomer Narrower
Fenclonine Hydrobromide Narrower
Fenclonine Hydrochloride Narrower
CP-10,188 Narrower
Fenclonine (L)-Isomer Narrower
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