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Glutathione Reductase
MeSH Descriptor Data 2025
Details
Qualifiers
MeSH Tree Structures
Concepts
MeSH Heading
Glutathione Reductase
Tree Number(s)
D08.811.682.667.092
Unique ID
D005980
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D005980
Scope Note
Catalyzes the oxidation of
GLUTATHIONE
to
GLUTATHIONE DISULFIDE
in the presence of
NADP
+. Deficiency in the enzyme is associated with
HEMOLYTIC ANEMIA
. Formerly listed as EC 1.6.4.2.
Entry Term(s)
Glutathione-Disulfide Reductase
CAS Type 1 Name
NADPH:oxidized-glutathione oxidoreductase
Public MeSH Note
65
History Note
65
Date Established
1965/01/01
Date of Entry
1999/01/01
Revision Date
2005/06/30
Allowable Qualifiers
administration & dosage (AD)
adverse effects (AE)
analysis (AN)
antagonists & inhibitors (AI)
biosynthesis (BI)
blood (BL)
cerebrospinal fluid (CF)
chemical synthesis (CS)
chemistry (CH)
classification (CL)
deficiency (DF)
drug effects (DE)
economics (EC)
genetics (GE)
history (HI)
immunology (IM)
isolation & purification (IP)
metabolism (ME)
pharmacokinetics (PK)
pharmacology (PD)
physiology (PH)
poisoning (PO)
radiation effects (RE)
standards (ST)
supply & distribution (SD)
therapeutic use (TU)
toxicity (TO)
ultrastructure (UL)
urine (UR)
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Oxidoreductases [D08.811.682]
Oxidoreductases Acting on Sulfur Group Donors [D08.811.682.667]
Dihydrolipoamide Dehydrogenase [D08.811.682.667.061]
Ferredoxin-NADP Reductase [D08.811.682.667.076]
Glutaredoxins [D08.811.682.667.084]
Glutathione Reductase [D08.811.682.667.092]
Hydrogensulfite Reductase [D08.811.682.667.124]
Protein Disulfide Reductase (Glutathione) [D08.811.682.667.186]
Sulfite Dehydrogenase [D08.811.682.667.217]
Sulfite Oxidase [D08.811.682.667.249]
Sulfite Reductase (Ferredoxin) [D08.811.682.667.374]
Sulfite Reductase (NADPH) [D08.811.682.667.500]
Thioredoxin-Disulfide Reductase [D08.811.682.667.750]
Expand All
Collapse All
Glutathione Reductase
Preferred
Concept UI
M0009393
Scope Note
Catalyzes the oxidation of
GLUTATHIONE
to
GLUTATHIONE DISULFIDE
in the presence of
NADP
+. Deficiency in the enzyme is associated with
HEMOLYTIC ANEMIA
. Formerly listed as EC 1.6.4.2.
Terms
Glutathione Reductase
Preferred Term
Term UI
T018120
Date
01/01/1999
LexicalTag
NON
ThesaurusID
NLM (1965)
Glutathione-Disulfide Reductase
Term UI
T631705
Date
02/27/2005
LexicalTag
NON
ThesaurusID
NLM (2006)
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