MeSH Browser

MeSH Heading: Protein Disulfide Reductase (Glutathione)
Tree Number(s): D08.811.682.667.186
Unique ID: D011490
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D011490
Scope Note: An enzyme that catalyzes the reduction of a protein-disulfide in the presence of glutathione, forming a protein-dithiol. Insulin is one of its substrates. EC 1.8.4.2.
Entry Term(s): Glutathione Insulin Transhydrogenase; Glutathione Protein Disulfide Oxidoreductase; Thiol-Disulfide Oxidoreductase; Thiol-Protein Disulfide Oxidoreductase
Registry Numbers: EC 1.8.4.2; 0
CAS Type 1 Name: Glutathione:protein-disulfide oxidoreductase
Previous Indexing: Glutathione (1972-1974); Glutathione Reductase (1974); Insulin (1972-1974); Oxidoreductases (1972-1974)
Public MeSH Note: 91; was see under OXIDOREDUCTASES 1975-90
History Note: 91(75); was see under OXIDOREDUCTASES 1975-90
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2005/06/30

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0017857
Registry Numbers: EC 1.8.4.2
Scope Note: An enzyme that catalyzes the reduction of a protein-disulfide in the presence of glutathione, forming a protein-dithiol. Insulin is one of its substrates. EC 1.8.4.2.
Terms: Protein Disulfide Reductase (Glutathione) Preferred Term
Term UI T033934
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1975); Glutathione Insulin Transhydrogenase
Term UI T033932
Date11/11/1974
LexicalTag NON
ThesaurusID UNK (19XX); Glutathione Protein Disulfide Oxidoreductase
Term UI T033933
Date11/11/1974
LexicalTag NON
ThesaurusID UNK (19XX); Thiol-Protein Disulfide Oxidoreductase
Term UI T033935
Date08/30/1982
LexicalTag NON
ThesaurusID UNK (19XX)

Protein Disulfide Reductase (Glutathione) MeSH Descriptor Data 2025