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Glutaredoxins MeSH Descriptor Data 2025


MeSH Heading
Glutaredoxins
Tree Number(s)
D08.811.682.667.084
Unique ID
D054477
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D054477
Scope Note
A family of thioltransferases that contain two active site CYSTEINE residues, which either form a disulfide (oxidized form) or a dithiol (reduced form). They function as an electron carrier in the GLUTHIONE-dependent synthesis of deoxyribonucleotides by RIBONUCLEOTIDE REDUCTASES and may play a role in the deglutathionylation of protein thiols. The oxidized forms of glutaredoxins are directly reduced by the GLUTATHIONE.
Entry Term(s)
Glutaredoxin
Glutaredoxin 1
Glutaredoxin 2
Glutaredoxin 3
Glutaredoxin 5
TTase-1
Thioltransferase
Thioltransferase-1
Registry Numbers
0
Public MeSH Note
2008; GLUTAREDOXINS were indexed under OXIDOREDUCTASES 2005-2007 & under PROTEINS 1979-2004; THIOLTRANSFERASE was indexed under SULFHYDRYL COMPOUNDS 1978-1981; under OXIDOREDUCTASES 1982-2004 & under PROTEIN DISULFIDE REDUCTASE (GLUTATHIONE) 2005-2007
History Note
2008(1980); use PROTEINS 1979
Date Established
2008/01/01
Date of Entry
2007/07/09
Revision Date
1955/01/01
Glutaredoxins Preferred
Glutaredoxin 1 Narrower
Glutaredoxin 2 Narrower
Glutaredoxin 3 Narrower
Glutaredoxin 5 Narrower
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