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Bisbenzimidazole MeSH Descriptor Data 2023


MeSH Heading
Bisbenzimidazole
Tree Number(s)
D03.633.100.103.145
Unique ID
D006690
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D006690
Scope Note
A benzimidazole antifilarial agent; it is fluorescent when it binds to certain nucleotides in DNA, thus providing a tool for the study of DNA replication; it also interferes with mitosis.
Entry Term(s)
4-(5-(4-Methyl-1-piperazinyl)(2,5'-bi-1H-benzimidazol)-2'-yl)phenol, trihydrochloride
Bisbenzimidazole Trihydrochloride
Bisbenzimide
Hoe-33258
Hoechst 33258
NSC-322921
Pibenzimol
Pharm Action
Filaricides
Fluorescent Dyes
Registry Number
LHQ7J5KV9B
Related Numbers
23491-44-3
23491-45-4
CAS Type 1 Name
4-(5-(5-(4-Methylpiperazin-1-yl)benzimidazol-2- yl)benzimidazol-2-yl)phenol
Previous Indexing
Benzimidazoles (1971-1976)
Phenols (1972-1975)
Piperazines (1971-1975)
Public MeSH Note
2008; see BISBENZIMIDE 1991-2008, see BENZIMIDAZOLES 1977-1990
History Note
2008(1977)
Date Established
1991/01/01
Date of Entry
1976/04/13
Revision Date
2016/05/27
Bisbenzimidazole Preferred
NSC-322921 Narrower
Bisbenzimidazole Trihydrochloride Narrower
Hoechst 33258 Narrower
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