MeSH Browser

MeSH Heading: Mibefradil
Tree Number(s): D02.455.426.559.847.638.960.585; D03.633.100.103.618; D04.615.638.960.585
Unique ID: D020748
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D020748
Scope Note: A benzimidazoyl-substituted tetraline that selectively binds and inhibits CALCIUM CHANNELS, T-TYPE.
Entry Term(s): Mibefradil Dihydrochloride; Posicor; Ro 40-5967
Pharm Action: Antihypertensive Agents
Calcium Channel Blockers
Vasodilator Agents
Cytochrome P-450 CYP1A2 Inhibitors
Related Numbers: 116644-53-2; 116666-63-8; 842TUP3PQ8
CAS Type 1 Name: (1S,2S)-(2-((3-(2-benzimidazolyl)propyl)methylamino)ethyl)-6-fluoro-1,2,3,4-tetrahydro-1-isopropyl-2-naphthyl methoxyacetate
Previous Indexing: Benzimidazoles (1989-1999); Tetrahydronaphthalenes (1989-1999)
Public MeSH Note: 2000; MIBEFRADIL was indexed under BENZIMIDAZOLES & TETRAHYDRONAPHTHALENS 1989-1999
History Note: 2000; use MIBEFRADIL 1989-1999
Date Established: 2000/01/01
Date of Entry: 1999/11/03
Revision Date: 2017/05/24

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Mibefradil MeSH Descriptor Data 2025