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Pimozide MeSH Descriptor Data 2025


MeSH Heading
Pimozide
Tree Number(s)
D03.633.100.103.732
Unique ID
D010868
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D010868
Scope Note
A diphenylbutylpiperidine that is effective as an antipsychotic agent and as an alternative to HALOPERIDOL for the suppression of vocal and motor tics in patients with Tourette syndrome. Although the precise mechanism of action is unknown, blockade of postsynaptic dopamine receptors has been postulated. (From AMA Drug Evaluations Annual, 1994, p403)
Entry Term(s)
Antalon
Orap
Orap forte
R-6238
Pharm Action
Antipsychotic Agents
Dopamine Antagonists
Anti-Dyskinesia Agents
Related Numbers
2062-78-4
CAS Type 1 Name
2H-Benzimidazol-2-one, 1-(1-(4,4-bis(4-fluorophenyl)butyl)-4-piperidinyl)-1,3-dihydro-
Previous Indexing
Benzimidazoles (1966-1972)
Tranquilizing Agents (1966-1972)
Public MeSH Note
73
History Note
73
Date Established
1973/01/01
Date of Entry
1999/01/01
Revision Date
2017/05/24
Pimozide Preferred
R-6238 Narrower
Antalon Narrower
Orap Narrower
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