MeSH Browser

MeSH Heading: Hydroxyurea
Tree Number(s): D02.065.950.395
Unique ID: D006918
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D006918
Scope Note: An antineoplastic agent that inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.
Entry Term(s): Hydrea; Hydroxycarbamid; Oncocarbide
Pharm Action: Antineoplastic Agents
Antisickling Agents
Enzyme Inhibitors
Nucleic Acid Synthesis Inhibitors
Related Numbers: 127-07-1
CAS Type 1 Name: Urea, hydroxy-
Previous Indexing: Antineoplastic Agents (1966); Urea (1966)
Public MeSH Note: 68
History Note: 68(67)
Date Established: 1968/01/01
Date of Entry: 1999/01/01
Revision Date: 2020/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Hydroxyurea MeSH Descriptor Data 2025