MeSH Browser

MeSH Heading: Orotate Phosphoribosyltransferase
Tree Number(s): D08.811.913.400.725.700
Unique ID: D009962
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D009962
Annotation: /defic: consider also OROTIC ACID /‌urine (IM) + PURINE-PYRIMIDINE METABOLISM, INBORN ERRORS (IM)
Scope Note: The enzyme catalyzing the formation of orotidine-5'-phosphoric acid (orotidylic acid) from orotic acid and 5-phosphoribosyl-1-pyrophosphate in the course of pyrimidine nucleotide biosynthesis. EC 2.4.2.10.
Entry Term(s): OMPase; Orotidine-5'-Monophosphate Phosphohydrolase; Orotidine-5'-Phosphate Pyrophosphorylase; Orotidylic Acid Phosphorylase
Registry Number: EC 2.4.2.10
Related Numbers: 9030-25-5
CAS Type 1 Name: Orotidine-5'-phosphate:pyrophosphate phospho-alpha-D-ribosyltransferase
Previous Indexing: Pentosyltransferases (1972-1976); Pyrimidine Nucleotides (1972-1974); Ribonucleotides (1972-1974); Uracil Nucleotides (1975-1976)
Public MeSH Note: 91; was see under PENTOSYLTRANSFERASES 1977-90
History Note: 91(77); was see under PENTOSYLTRANSFERASES 1977-90
Date Established: 1991/01/01
Date of Entry: 1976/04/27
Revision Date: 2003/07/09

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0015445
Registry Number: EC 2.4.2.10
Related Numbers: 9030-25-5
Scope Note: The enzyme catalyzing the formation of orotidine-5'-phosphoric acid (orotidylic acid) from orotic acid and 5-phosphoribosyl-1-pyrophosphate in the course of pyrimidine nucleotide biosynthesis. EC 2.4.2.10.
Terms: Orotate Phosphoribosyltransferase Preferred Term
Term UI T029472
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1977); Orotidylic Acid Phosphorylase
Term UI T029475
Date04/26/1976
LexicalTag NON
ThesaurusID UNK (19XX); Orotidine-5'-Phosphate Pyrophosphorylase
Term UI T029474
Date04/26/1976
LexicalTag NON
ThesaurusID UNK (19XX); OMPase
Term UI T029471
Date05/19/1982
LexicalTag NON
ThesaurusID UNK (19XX); Orotidine-5'-Monophosphate Phosphohydrolase
Term UI T029473
Date05/19/1982
LexicalTag NON
ThesaurusID UNK (19XX)

Orotate Phosphoribosyltransferase MeSH Descriptor Data 2023