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Papillon-Lefevre Disease MeSH Descriptor Data 2023


MeSH Heading
Papillon-Lefevre Disease
Tree Number(s)
C16.320.850.475.600
C17.800.428.435.600
C17.800.827.475.600
Unique ID
D010214
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D010214
Scope Note
Rare, autosomal recessive disorder occurring between the first and fifth years of life. It is characterized by palmoplantar keratoderma with periodontitis followed by the premature shedding of both deciduous and permanent teeth. Mutations in the gene for CATHEPSIN C have been associated with this disease.
Entry Version
PAPILLON LEFEVRE DIS
Entry Term(s)
Haim-Monk Syndrome
Keratosis Palmoplantar Periodontopathy
Keratosis Palmoplantaris with Periodontopathia
Papillon Lefevre Disease
Papillon-Lefevre Syndrome
See Also
Cathepsin C
Public MeSH Note
91; was see under KERATOSIS PALMARIS ET PLANTARIS 1975-90 (which became KERATODERMA, PALMOPLANTAR 1993)
Online Note
search KERATODERMA, PALMOPLANTAR 1974
History Note
91(75); was see under KERATOSIS PALMARIS ET PLANTARIS 1975-90 (which became KERATODERMA, PALMOPLANTAR 1993)
Date Established
1991/01/01
Date of Entry
1999/01/01
Revision Date
2015/06/22
Papillon-Lefevre Disease Preferred
Haim-Monk Syndrome Related
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