MeSH Browser

MeSH Heading: Papillon-Lefevre Disease
Tree Number(s): C16.320.850.475.600; C17.800.428.435.600; C17.800.827.475.600
Unique ID: D010214
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D010214
Scope Note: Rare, autosomal recessive disorder occurring between the first and fifth years of life. It is characterized by palmoplantar keratoderma with periodontitis followed by the premature shedding of both deciduous and permanent teeth. Mutations in the gene for CATHEPSIN C have been associated with this disease.
Entry Version: PAPILLON LEFEVRE DIS
Entry Term(s): Haim-Monk Syndrome; Keratosis Palmoplantar Periodontopathy; Keratosis Palmoplantaris with Periodontopathia; Papillon Lefevre Disease; Papillon-Lefevre Syndrome
See Also: Cathepsin C
Public MeSH Note: 91; was see under KERATOSIS PALMARIS ET PLANTARIS 1975-90 (which became KERATODERMA, PALMOPLANTAR 1993)
Online Note: search KERATODERMA, PALMOPLANTAR 1974
History Note: 91(75); was see under KERATOSIS PALMARIS ET PLANTARIS 1975-90 (which became KERATODERMA, PALMOPLANTAR 1993)
Date Established: 1991/01/01
Date of Entry: 1999/01/01
Revision Date: 2015/06/22

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

veterinary (VE)

virology (VI)

Concept UI: M0015840
Scope Note: Rare, autosomal recessive disorder occurring between the first and fifth years of life. It is characterized by palmoplantar keratoderma with periodontitis followed by the premature shedding of both deciduous and permanent teeth. Mutations in the gene for CATHEPSIN C have been associated with this disease.
Terms: Papillon-Lefevre Disease Preferred Term
Term UI T030200
Date01/01/1999
LexicalTag EPO
ThesaurusID; Papillon-Lefevre Syndrome
Term UI T030201
Date04/03/1992
LexicalTag EPO
ThesaurusID; Keratosis Palmoplantar Periodontopathy
Term UI T746750
Date02/27/2009
LexicalTag NON
ThesaurusID ORD (2010); Keratosis Palmoplantaris with Periodontopathia
Term UI T746751
Date02/27/2009
LexicalTag NON
ThesaurusID; Papillon Lefevre Disease
Term UI T746752
Date02/27/2009
LexicalTag EPO
ThesaurusID ORD (2010)

Papillon-Lefevre Disease MeSH Descriptor Data 2025