MeSH Browser

MeSH Heading: Bulbar Palsy, Progressive
Tree Number(s): C10.574.562.300; C10.668.467.300
Unique ID: D010244
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D010244
Scope Note: A motor neuron disease marked by progressive weakness of the muscles innervated by cranial nerves of the lower brain stem. Clinical manifestations include dysarthria, dysphagia, facial weakness, tongue weakness, and fasciculations of the tongue and facial muscles. The adult form of the disease is marked initially by bulbar weakness which progresses to involve motor neurons throughout the neuroaxis. Eventually this condition may become indistinguishable from AMYOTROPHIC LATERAL SCLEROSIS. Fazio-Londe syndrome is an inherited form of this illness which occurs in children and young adults. (Adams et al., Principles of Neurology, 6th ed, p1091; Brain 1992 Dec;115(Pt 6):1889-1900)
Entry Term(s): Bulbar Palsy; Bulbar Palsy, Progressive, Of Childhood; Childhood Progressive Bulbar Palsy; Fazio-Londe Disease; Fazio-Londe Syndrome; Paralysis, Bulbar; Progressive Bulbar Palsy of Childhood
NLM Classification #: WL 310
Public MeSH Note: 2000; see PARALYSIS, BULBAR 1966-1999
History Note: 2000(1966)
Date Established: 2000/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/06/08

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Bulbar Palsy, Progressive MeSH Descriptor Data 2022