MeSH Browser

MeSH Heading: Muscular Atrophy, Spinal
Tree Number(s): C10.228.854.468; C10.574.562.500; C10.668.467.500
Unique ID: D009134
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D009134
Annotation: MUSCULAR ATROPHY, SPINAL, INFANTILE see SPINAL MUSCULAR ATROPHIES OF CHILDHOOD is also available
Scope Note: A group of disorders marked by progressive degeneration of motor neurons in the spinal cord resulting in weakness and muscular atrophy, usually without evidence of injury to the corticospinal tracts. Diseases in this category include Werdnig-Hoffmann disease and later onset SPINAL MUSCULAR ATROPHIES OF CHILDHOOD, most of which are hereditary. (Adams et al., Principles of Neurology, 6th ed, p1089)
Entry Term(s): Adult Spinal Muscular Atrophy; Adult-Onset Spinal Muscular Atrophy; Amyotrophy, Neurogenic Scapuloperoneal, New England Type; Bulbospinal Neuronopathy; Distal Spinal Muscular Atrophy; Hereditary Motor Neuronopathy; Muscular Atrophy, Adult Spinal; Myelopathic Muscular Atrophy; Myelopathic Muscular Atrophy, Progressive; Oculopharyngeal Spinal Muscular Atrophy; Progressive Muscular Atrophy; Progressive Myelopathic Muscular Atrophy; Progressive Proximal Myelopathic Muscular Atrophy; Proximal Myelopathic Muscular Atrophy, Progressive; Scapuloperoneal Form of Spinal Muscular Atrophy; Scapuloperoneal Spinal Muscular Atrophy; Spinal Amyotrophy; Spinal Muscular Atrophy; Spinal Muscular Atrophy, Distal; Spinal Muscular Atrophy, Oculopharyngeal; Spinal Muscular Atrophy, Scapuloperoneal; Spinal Muscular Atrophy, Scapuloperoneal Form
NLM Classification #: WE 550
Previous Indexing: Muscular Atrophy (1966-1987); Spinal Cord Diseases (1966-1987)
Public MeSH Note: 1988
History Note: 1988
Date Established: 1988/01/01
Date of Entry: 1987/03/10
Revision Date: 2015/06/23

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

congenital (CN)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

veterinary (VE)

virology (VI)

Nervous System Diseases [C10]
- Central Nervous System Diseases [C10.228]
  - Spinal Cord Diseases [C10.228.854]

Nervous System Diseases [C10]
- Neurodegenerative Diseases [C10.574]
  - Motor Neuron Disease [C10.574.562]

Nervous System Diseases [C10]
- Neuromuscular Diseases [C10.668]
  - Motor Neuron Disease [C10.668.467]

Muscular Atrophy, Spinal Preferred

Concept UI: M0014250
Scope Note: A group of disorders marked by progressive degeneration of motor neurons in the spinal cord resulting in weakness and muscular atrophy, usually without evidence of injury to the corticospinal tracts. Diseases in this category include Werdnig-Hoffmann disease and later onset SPINAL MUSCULAR ATROPHIES OF CHILDHOOD, most of which are hereditary. (Adams et al., Principles of Neurology, 6th ed, p1089)
Terms: Muscular Atrophy, Spinal Preferred Term
Term UI T027301
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1988); Spinal Muscular Atrophy
Term UI T027300
Date03/10/1987
LexicalTag NON
ThesaurusID; Spinal Amyotrophy
Term UI T842508
Date04/18/2013
LexicalTag NON
ThesaurusID GHR (2014)

Myelopathic Muscular Atrophy Narrower

Bulbospinal Neuronopathy Narrower

Oculopharyngeal Spinal Muscular Atrophy Narrower

Scapuloperoneal Form of Spinal Muscular Atrophy Narrower

Distal Spinal Muscular Atrophy Narrower

Progressive Proximal Myelopathic Muscular Atrophy Narrower

Progressive Muscular Atrophy Narrower

Hereditary Motor Neuronopathy Narrower

Muscular Atrophy, Spinal MeSH Descriptor Data 2025