MeSH Browser

MeSH Heading: Saxitoxin
Tree Number(s): D03.633.100.759.794; D20.888.590.662; D23.946.123.257.750; D23.946.580.590.662; D23.946.580.830; D23.946.833.590.662
Unique ID: D012530
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D012530
Annotation: /antag permitted but consider also ANTITOXINS
Scope Note: A compound that contains a reduced purine ring system but is not biosynthetically related to the purine alkaloids. It is a poison found in certain edible mollusks at certain times; elaborated by GONYAULAX and consumed by mollusks, fishes, etc. without ill effects. It is neurotoxic and causes RESPIRATORY PARALYSIS and other effects in MAMMALS, known as paralytic SHELLFISH poisoning.
Entry Term(s): Gonyaulax Toxin; Mitilotoxin; Saxitonin
Pharm Action: Poisons
CAS Type 1 Name: 1H,10H-Pyrrolo(1,2-c)purine-10,10-diol, 2,6-diamino-4-(((aminocarbonyl)oxy)methyl)-3a,4,8,9-tetrahydro-, (3aS-(3aalpha,4alpha,10aR*))-
Public MeSH Note: 74
History Note: 74
Date Established: 1974/01/01
Date of Entry: 1999/01/01
Revision Date: 2021/05/10

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0019455
Scope Note: A compound that contains a reduced purine ring system but is not biosynthetically related to the purine alkaloids. It is a poison found in certain edible mollusks at certain times; elaborated by GONYAULAX and consumed by mollusks, fishes, etc. without ill effects. It is neurotoxic and causes RESPIRATORY PARALYSIS and other effects in MAMMALS, known as paralytic SHELLFISH poisoning.
Terms: Saxitoxin Preferred Term
Term UI T037169
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1974); Gonyaulax Toxin
Term UI T037166
Date04/14/1977
LexicalTag NON
ThesaurusID UNK (19XX); Mitilotoxin
Term UI T037167
Date10/23/1981
LexicalTag NON
ThesaurusID UNK (19XX); Saxitonin
Term UI T037168
Date08/10/1987
LexicalTag NON
ThesaurusID UNK (19XX)

Saxitoxin MeSH Descriptor Data 2025