MeSH Browser

MeSH Heading: Glycine Hydroxymethyltransferase
Tree Number(s): D08.811.913.555.400.500
Unique ID: D012696
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D012696
Scope Note: A pyridoxal phosphate enzyme that catalyzes the reaction of glycine and 5,10-methylene-tetrahydrofolate to form serine. It also catalyzes the reaction of glycine with acetaldehyde to form L-threonine. EC 2.1.2.1.
Entry Term(s): Allothreonine Aldolase; Serine Aldolase; Serine Hydroxymethylase; Serine Hydroxymethyltransferase; Serine Transhydroxymethylase; Threonine Aldolase
Related Numbers: 9029-83-8
CAS Type 1 Name: 5,10-Methylenetetrahydrofolate:glycine hydroxymethyltransferase
Previous Indexing: Serine (1973-1974); Tetrahydrofolates (1973-1974); Transferases (1973-1974)
Public MeSH Note: 98; see SERINE HYDROXYMETHYLTRANSFERASE 1991-97, see TRANSFERASES 1975-90
History Note: 98(75)
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2003/07/09

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0019677
Related Numbers: 9029-83-8
Scope Note: A pyridoxal phosphate enzyme that catalyzes the reaction of glycine and 5,10-methylene-tetrahydrofolate to form serine. It also catalyzes the reaction of glycine with acetaldehyde to form L-threonine. EC 2.1.2.1.
Terms: Glycine Hydroxymethyltransferase Preferred Term
Term UI T037536
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1975); Allothreonine Aldolase
Term UI T037530
Date04/27/1981
LexicalTag NON
ThesaurusID UNK (19XX); Threonine Aldolase
Term UI T037535
Date11/11/1974
LexicalTag NON
ThesaurusID UNK (19XX); Serine Hydroxymethylase
Term UI T037532
Date11/11/1974
LexicalTag NON
ThesaurusID UNK (19XX); Serine Hydroxymethyltransferase
Term UI T037533
Date12/03/1996
LexicalTag NON
ThesaurusID NLM (1998); Serine Transhydroxymethylase
Term UI T037534
Date11/11/1974
LexicalTag NON
ThesaurusID UNK (19XX); Serine Aldolase
Term UI T037531
Date11/11/1974
LexicalTag NON
ThesaurusID UNK (19XX)

Glycine Hydroxymethyltransferase MeSH Descriptor Data 2025