MeSH Browser

MeSH Heading: Phosphoribosylaminoimidazolecarboxamide Formyltransferase
Tree Number(s): D08.811.913.555.400.625
Unique ID: D051027
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D051027
Scope Note: An enzyme that catalyzes the conversion of aminoimidazole-4-carboxamide ribonucleotide to 5-formyl-aminoimidazole-4-carboxamide ribonucleotide in the purine de novo synthesis pathway. It requires the cofactor N(10)-FORMYLTETRAHYDROFOLATE as the formyl donor.
Entry Term(s): AICAR Formyltransferase; AICAR Transformylase; AICARTFase; Aminoimidazolecarboxamide Ribonucleotide Transformylase
Registry Numbers: EC 2.1.2.3
Related Numbers: 9032-03-5
CAS Type 1 Name: 5-amino-4-imidazolecarboxamide ribotide transformylase
Public MeSH Note: 2006; PHOSPHORIBOSYLAMINOIMIDAZOLECARBOXAMIDE FORMYLTRANSFERASE was indexed under HYDROXYMETHYL AND FORMYL TRANSFERASES 1998-2005, ACYLTRANSFERASES 1980-1997, FORMIC ACIDS 1974-1980, AMINOIMIDAZOLE CARBOXAMIDE 1979-1980, IMIDAZOLES 1974-1979, PENTOSEPHOSPHATES 1974-1979, TRANSFERASES 1974-1979
History Note: 2006(1980); use FORMIC ACIDS 1974-1980, AMINOIMIDAZOLE CARBOXAMIDE 1979-1980, IMIDAZOLES 1974-1979, PENTOSEPHOSPHATES 1974-1979, TRANSFERASES 1974-1979
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2009/07/15

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0078323
Registry Numbers: EC 2.1.2.3
Related Numbers: 9032-03-5
Scope Note: An enzyme that catalyzes the conversion of aminoimidazole-4-carboxamide ribonucleotide to 5-formyl-aminoimidazole-4-carboxamide ribonucleotide in the purine de novo synthesis pathway. It requires the cofactor N(10)-FORMYLTETRAHYDROFOLATE as the formyl donor.
Terms: Phosphoribosylaminoimidazolecarboxamide Formyltransferase Preferred Term
Term UI T108326
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006); Aminoimidazolecarboxamide Ribonucleotide Transformylase
Term UI T108325
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006); AICAR Formyltransferase
Term UI T108322
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2006); AICAR Transformylase
Term UI T108323
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2006); AICARTFase
Term UI T108324
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2006)

Phosphoribosylaminoimidazolecarboxamide Formyltransferase MeSH Descriptor Data 2025