MeSH Browser

MeSH Heading: Phosphoribosylglycinamide Formyltransferase
Tree Number(s): D08.811.913.555.400.750
Unique ID: D051026
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D051026
Scope Note: An enzyme that catalyzes the transfer of a formyl group from N10-formyltetrahydrofolate to N1-(5-phospho-D-ribosyl)glycinamide to yield N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and tetrahydrofolate. It plays a role in the de novo purine biosynthetic pathway.
Entry Term(s): 2-Amino-N-Ribosylacetamide 5'-Phosphate Transformylase; 5'-Phosphoribosylglycinamide Transformylase; GAR Formyltransferase; GAR Transformylase; GARTFase; Glycinamide Ribonucleotide Transformylase; Glycinamideribotide Transformylase
Related Numbers: 9032-02-4
Public MeSH Note: 2006; PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE was indexed under HYDROXYMETHYL AND FORMYL TRANSFERASES 1998-2005, ACYLTRANSFERASES 1979-1997, GLYCINE 1974-1980, FORMIC ACIDS 1974-1982, GLYCINE 1980-1982, PENTOSEPHOSPHATES 1974-1975, RIBOSEMONOPHOSPHATES 1975-1980, & under TRANSFERASES 1974-1978
History Note: 2006(1980); use ACYLTRANSFERASES 1979, GLYCINE 1974-1979, FORMIC ACIDS 1974-1979, PENTOSEPHOSPHATES 1974-1975, RIBOSEMONOPHOSPHATES 1975-1979, & TRANSFERASES 1974-1978
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2013/07/09

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0078358
Related Numbers: 9032-02-4
Scope Note: An enzyme that catalyzes the transfer of a formyl group from N10-formyltetrahydrofolate to N1-(5-phospho-D-ribosyl)glycinamide to yield N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and tetrahydrofolate. It plays a role in the de novo purine biosynthetic pathway.
Terms: Phosphoribosylglycinamide Formyltransferase Preferred Term
Term UI T108361
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006); Glycinamide Ribonucleotide Transformylase
Term UI T108357
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006); Glycinamideribotide Transformylase
Term UI T108358
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006); 2-Amino-N-Ribosylacetamide 5'-Phosphate Transformylase
Term UI T627065
Date01/06/2005
LexicalTag NON
ThesaurusID NLM (2006); GARTFase
Term UI T108356
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2006); GAR Formyltransferase
Term UI T627066
Date01/06/2005
LexicalTag ABX
ThesaurusID NLM (2006); GAR Transformylase
Term UI T108354
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2006); 5'-Phosphoribosylglycinamide Transformylase
Term UI T627064
Date01/06/2005
LexicalTag NON
ThesaurusID NLM (2006)

Phosphoribosylglycinamide Formyltransferase MeSH Descriptor Data 2025