NLM Logo

Sulindac MeSH Descriptor Data 2022


MeSH Heading
Sulindac
Tree Number(s)
D02.455.426.559.847.486.875
D04.615.486.875
Unique ID
D013467
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D013467
Scope Note
A sulfinylindene derivative prodrug whose sulfinyl moiety is converted in vivo to an active NSAID analgesic. Specifically, the prodrug is converted by liver enzymes to a sulfide which is excreted in the bile and then reabsorbed from the intestine. This helps to maintain constant blood levels with reduced gastrointestinal side effects.
Entry Term(s)
Aclin
Apo-Sulin
Arthrobid
Arthrocine
Chibret
Clinoril
Copal
Kenalin
Klinoril
MK-231
Novo-Sundac
Nu-Sulindac
Sulindal
Pharm Action
Anti-Inflammatory Agents, Non-Steroidal
Antineoplastic Agents
Cyclooxygenase Inhibitors
Registry Number
184SNS8VUH
Related Numbers
38194-50-2
CAS Type 1 Name
1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-, (Z)-
Previous Indexing
Benzene (1966-1967)
Benzene Derivatives (1968-1974)
Benzylidene Compounds (1975-1978)
Indenes (1966-1978)
Public MeSH Note
90; was see under INDENES 1979-89
History Note
90(79); was see under INDENES 1979-89
Date Established
1990/01/01
Date of Entry
1978/02/08
Revision Date
2016/07/01
Sulindac Preferred
Apo-Sulin Narrower
Arthrobid Narrower
Clinoril Narrower
Sulindal Narrower
Kenalin Narrower
MK-231 Narrower
Novo-Sundac Narrower
Nu-Sulindac Narrower
Aclin Narrower
Copal Narrower
page delivered in 0.148s