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Tamoxifen MeSH Descriptor Data 2021


MeSH Heading
Tamoxifen
Tree Number(s)
D02.455.426.559.389.150.700.900
Unique ID
D013629
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D013629
Scope Note
One of the SELECTIVE ESTROGEN RECEPTOR MODULATORS with tissue-specific activities. Tamoxifen acts as an anti-estrogen (inhibiting agent) in the mammary tissue, but as an estrogen (stimulating agent) in cholesterol metabolism, bone density, and cell proliferation in the ENDOMETRIUM.
Entry Term(s)
ICI-46,474
ICI-46474
ICI-47699
Nolvadex
Novaldex
Soltamox
Tamoxifen Citrate
Tomaxithen
Zitazonium
Pharm Action
Estrogen Antagonists
Antineoplastic Agents, Hormonal
Selective Estrogen Receptor Modulators
Bone Density Conservation Agents
Registry Number
094ZI81Y45
Related Numbers
10540-29-1
54965-24-1
7FRV7310N6
CAS Type 1 Name
Ethanamine, 2-(4-(1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethyl-, (Z)-
Previous Indexing
Dimethylamines (1973-1974)
Phenyl Ethers (1974)
Stilbenes (1966-1974)
Public MeSH Note
78; was see under STILBENES 1975-77
History Note
78(75); was see under STILBENES 1975-77
Date Established
1978/01/01
Date of Entry
1974/11/11
Revision Date
2016/07/01
Tamoxifen Preferred
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Nolvadex Narrower
Tamoxifen Citrate Narrower
Tomaxithen Narrower
Zitazonium Narrower
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