MeSH Browser

MeSH Heading: Raloxifene Hydrochloride
Tree Number(s): D02.455.426.559.389.150.700.900.775
Unique ID: D020849
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D020849
Scope Note: A second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women. It has estrogen agonist effects on bone and cholesterol metabolism but behaves as a complete estrogen antagonist on mammary gland and uterine tissue.
Entry Term(s): Evista; Keoxifene; Keoxifene Hydrochloride; LY 139481; LY 156758; LY-139481; LY-156758; Raloxifene; Raloxifene HCl
Pharm Action: Estrogen Antagonists
Selective Estrogen Receptor Modulators
Bone Density Conservation Agents
Registry Numbers: 4F86W47BR6; 0; YX9162EO3I
Related Numbers: 82640-04-8; 84449-90-1; YX9162EO3I
Previous Indexing: Piperidines (1983-1999)
Public MeSH Note: 2000; LY 139481 (now RALOXIFENE) was indexed under PIPERIDINES 1983-1999
History Note: 2000; use RALOXIFENE (NM) 1983-1999
Date Established: 2000/01/01
Date of Entry: 1999/11/03
Revision Date: 2015/07/08

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0112969
Registry Numbers: 4F86W47BR6
Related Numbers: 82640-04-8; 84449-90-1; YX9162EO3I
Scope Note: A second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women. It has estrogen agonist effects on bone and cholesterol metabolism but behaves as a complete estrogen antagonist on mammary gland and uterine tissue.
Terms: Raloxifene Hydrochloride Preferred Term
Term UI T142973
Date10/12/1999
LexicalTag NON
ThesaurusID; Raloxifene HCl
Term UI T000877409
Date03/26/2015
LexicalTag NON
ThesaurusID NLM (2016); Keoxifene Hydrochloride
Term UI T365885
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000)

Raloxifene Hydrochloride MeSH Descriptor Data 2025