MeSH Browser

MeSH Heading: Tromethamine
Tree Number(s): D02.033.455.706.900
Unique ID: D014325
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D014325
Scope Note: An organic amine proton acceptor. It is used in the synthesis of surface-active agents and pharmaceuticals; as an emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, as a biological buffer, and used as an alkalizer. (From Merck, 11th ed; Martindale, The Extra Pharmacopoeia, 30th ed, p1424)
Entry Term(s): Tri(hydroxymethyl)aminomethane; Tris Buffer; Tris(hydroxymethyl)aminomethane; Tris-Magnesium(II)-Potassium Chloride Buffer; Tris-Mg(II)-KCl Buffer; Trisamine; Trizma; Trometamol
Pharm Action: Buffers
Excipients
Related Numbers: 77-86-1
CAS Type 1 Name: 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-
Public MeSH Note: 65
History Note: 65
Date Established: 1965/01/01
Date of Entry: 1999/01/01
Revision Date: 2017/02/24

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0022030
Related Numbers: 77-86-1
Scope Note: An organic amine proton acceptor. It is used in the synthesis of surface-active agents and pharmaceuticals; as an emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, as a biological buffer, and used as an alkalizer. (From Merck, 11th ed; Martindale, The Extra Pharmacopoeia, 30th ed, p1424)
Terms: Tromethamine Preferred Term
Term UI T041931
Date01/01/1999
LexicalTag NON
ThesaurusID; Tris(hydroxymethyl)aminomethane
Term UI T041927
Date08/18/1980
LexicalTag NON
ThesaurusID; Tris Buffer
Term UI T041928
Date01/01/1975
LexicalTag NON
ThesaurusID UNK (19XX); Trisamine
Term UI T041929
Date04/29/1977
LexicalTag NON
ThesaurusID UNK (19XX); Trometamol
Term UI T041930
Date04/29/1977
LexicalTag NON
ThesaurusID; Tri(hydroxymethyl)aminomethane
Term UI T041933
Date08/18/1980
LexicalTag NON
ThesaurusID UNK (19XX)

Tromethamine MeSH Descriptor Data 2025