MeSH Browser

MeSH Heading: Chloramphenicol
Tree Number(s): D02.033.455.706.300; D02.455.426.559.389.565.175; D02.640.529.175
Unique ID: D002701
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D002701
Annotation: an antibiotic
Scope Note: An antibiotic first isolated from cultures of Streptomyces venequelae in 1947 but now produced synthetically. It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It acts by interfering with bacterial protein synthesis and is mainly bacteriostatic. (From Martindale, The Extra Pharmacopoeia, 29th ed, p106)
Entry Term(s): Amphenicol; Amphenicols; Chlornitromycin; Chlorocid; Chloromycetin; Cloranfenicol; Detreomycin; Kloramfenikol; Levomycetin; Ophthochlor; Syntomycin
Pharm Action: Anti-Bacterial Agents
Protein Synthesis Inhibitors
Related Numbers: 56-75-7
CAS Type 1 Name: Acetamide, 2,2-dichloro-N-(2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl)-, (R-(R*,R*))-
NLM Classification #: QV 350.5.C5
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2018/07/02

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0004121
Related Numbers: 56-75-7
Scope Note: An antibiotic first isolated from cultures of Streptomyces venequelae in 1947 but now produced synthetically. It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It acts by interfering with bacterial protein synthesis and is mainly bacteriostatic. (From Martindale, The Extra Pharmacopoeia, 29th ed, p106)
Terms: Chloramphenicol Preferred Term
Term UI T007820
Date01/01/1999
LexicalTag NON
ThesaurusID; Cloranfenicol
Term UI T007821
Date03/30/1977
LexicalTag NON
ThesaurusID UNK (19XX); Kloramfenikol
Term UI T007822
Date03/30/1977
LexicalTag NON
ThesaurusID UNK (19XX)

Chloramphenicol MeSH Descriptor Data 2025