MeSH Browser

MeSH Heading: Fingolimod Hydrochloride
Tree Number(s): D02.033.100.700.350; D02.033.455.706.431; D02.092.063.700.350
Unique ID: D000068876
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000068876
Scope Note: A sphingosine-derivative and IMMUNOSUPPRESSIVE AGENT that blocks the migration and homing of LYMPHOCYTES to the CENTRAL NERVOUS SYSTEM through its action on SPHINGOSINE 1-PHOSPHATE RECEPTORS. It is used in the treatment of MULTIPLE SCLEROSIS.
Entry Term(s): 2-Amino-2-(2-(4-octylphenyl)ethyl)-1,3-propanediol hydrochloride; FTY 720; FTY-720; FTY720; Fingolimod; Gilenia; Gilenya
Pharm Action: Immunosuppressive Agents
Sphingosine 1 Phosphate Receptor Modulators
Registry Numbers: G926EC510T; 3QN8BYN5QF; 0
Related Numbers: 162359-56-0; 3QN8BYN5QF
Public MeSH Note: 2016; FINGOLIMOD HYDROCHLORIDE was indexed under PROPYLENE GLYCOLS and SPHINGOSINE 1996-2015
History Note: 2016 (1996)
Date Established: 2016/01/01
Date of Entry: 2015/07/06
Revision Date: 2019/06/17

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Fingolimod Hydrochloride MeSH Descriptor Data 2024