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Valproic Acid MeSH Descriptor Data 2021


MeSH Heading
Valproic Acid
Tree Number(s)
D02.241.081.944.509.900
D10.251.400.895.593.900
Unique ID
D014635
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D014635
Scope Note
A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
Entry Term(s)
2-Propylpentanoic Acid
Calcium Valproate
Convulsofin
Depakene
Depakine
Depakote
Dipropyl Acetate
Divalproex
Divalproex Sodium
Ergenyl
Magnesium Valproate
Propylisopropylacetic Acid
Semisodium Valproate
Sodium Valproate
Valproate
Valproate Calcium
Valproate Sodium
Valproic Acid, Sodium Salt (2:1)
Vupral
Pharm Action
Anticonvulsants
Enzyme Inhibitors
GABA Agents
Antimanic Agents
Registry Number
614OI1Z5WI
Related Numbers
56CCK4F86G
5VOM6GYJ0D
644VL95AO6
76584-70-8
99-66-1
Q400352CM2
CAS Type 1 Name
Pentanoic acid, 2-propyl-
NLM Classification #
QV 85
Previous Indexing
Valerates (1966-1974)
Public MeSH Note
1991; was VALPROATE 1979-1990; was DIPROPYL ACETATE see under VALERATES 1975-1978
Online Note
use VALPROIC ACID to search VALPROATE 1979-90 & DIPROPYL ACETATE 1975-90
History Note
1991; was VALPROATE 1979-1990; was DIPROPYL ACETATE see under VALERATES 1975-1978
Date Established
1979/01/01
Date of Entry
1974/11/11
Revision Date
2018/06/19
Valproic Acid Preferred
Depakene Narrower
Convulsofin Narrower
Depakote Narrower
Dipropyl Acetate Related
Divalproex Sodium Narrower
Vupral Narrower
Valproic Acid, Sodium Salt (2:1) Narrower
Propylisopropylacetic Acid Related
Ergenyl Narrower
Magnesium Valproate Narrower
Valproate Narrower
Valproate Sodium Narrower
Calcium Valproate Narrower
Depakine Narrower
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