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Fibrinogens, Abnormal MeSH Descriptor Data 2023


MeSH Heading
Fibrinogens, Abnormal
Tree Number(s)
D12.776.124.050.250.265
D12.776.124.125.500.265
D23.119.490.265
Unique ID
D015241
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D015241
Scope Note
Fibrinogens which have a functional defect as the result of one or more amino acid substitutions in the amino acid sequence of normal fibrinogen. Abnormalities of the fibrinogen molecule may impair any of the major steps involved in the conversion of fibrinogen into stabilized fibrin, such as cleavage of the fibrinopeptides by thrombin, polymerization and cross-linking of fibrin. The resulting dysfibrinogenemias can be clinically silent or can be associated with bleeding, thrombosis or defective wound healing.
Entry Version
FIBRINOGENS ABNORM
Entry Term(s)
Abnormal Fibrinogens
Registry Number
0
Previous Indexing
Fibrinogen (1966-1988)
Public MeSH Note
89
History Note
89
Date Established
1989/01/01
Date of Entry
1988/05/16
Revision Date
2018/06/30
Fibrinogens, Abnormal Preferred
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