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Leukemia, Myelogenous, Chronic, BCR-ABL Positive MeSH Descriptor Data 2023


MeSH Heading
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Tree Number(s)
C04.557.337.539.250
C15.378.190.636.370
C23.550.291.500.485
Unique ID
D015464
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D015464
Scope Note
Clonal hematopoetic disorder caused by an acquired genetic defect in PLURIPOTENT STEM CELLS. It starts in MYELOID CELLS of the bone marrow, invades the blood and then other organs. The condition progresses from a stable, more indolent, chronic phase (LEUKEMIA, MYELOID, CHRONIC PHASE) lasting up to 7 years, to an advanced phase composed of an accelerated phase (LEUKEMIA, MYELOID, ACCELERATED PHASE) and BLAST CRISIS.
Entry Term(s)
Granulocytic Leukemia, Chronic
Leukemia, Chronic Myelogenous
Leukemia, Chronic Myeloid
Leukemia, Granulocytic, Chronic
Leukemia, Myelocytic, Chronic
Leukemia, Myelogenous, Chronic
Leukemia, Myelogenous, Ph1 Positive
Leukemia, Myelogenous, Ph1-Positive
Leukemia, Myeloid, Chronic
Leukemia, Myeloid, Ph1 Positive
Leukemia, Myeloid, Ph1-Positive
Leukemia, Myeloid, Philadelphia Positive
Leukemia, Myeloid, Philadelphia-Positive
Myelocytic Leukemia, Chronic
Myelogenous Leukemia, Chronic
Myelogenous Leukemia, Ph1-Positive
Myeloid Leukemia, Chronic
Myeloid Leukemia, Ph1-Positive
Myeloid Leukemia, Philadelphia-Positive
NLM Classification #
WH 250
Previous Indexing
Leukemia, Myelocytic (1966-1988)
Leukemia, Myeloid (1966-1988)
Public MeSH Note
2008; see LEUKEMIA, MYELOID, CHRONIC 1989-2007; for LEUKEMIA, MYELOID, PHILADELPHIA-POSITIVE see LEUKEMIA, MYELOID, PHILADELPHIA-POSITIVE 1989-2007; for LEUKEMIA, MYELOCYTIC, CHRONIC & LEUKEMIA, MYELOGENOUS, CHRONIC see LEUKEMIA, MYELOCYTIC 1974-1988
History Note
2008 (1989); for LEUKEMIA, MYELOCYTIC, CHRONIC & LEUKEMIA, MYELOGENOUS, CHRONIC use LEUKEMIA, MYELOID 1974-1988
Date Established
1989/01/01
Date of Entry
1988/06/09
Revision Date
2021/03/12
Leukemia, Myelogenous, Chronic, BCR-ABL Positive Preferred
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