MeSH Browser

MeSH Heading: Macrophage Colony-Stimulating Factor
Tree Number(s): D09.400.430.775.500; D12.644.276.374.410.240.500; D12.776.395.240.500; D12.776.467.374.410.240.500; D23.529.374.410.240.500
Unique ID: D016173
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D016173
Scope Note: A mononuclear phagocyte colony-stimulating factor (M-CSF) synthesized by mesenchymal cells. The compound stimulates the survival, proliferation, and differentiation of hematopoietic cells of the monocyte-macrophage series. M-CSF is a disulfide-bonded glycoprotein dimer with a MW of 70 kDa. It binds to a specific high affinity receptor (RECEPTOR, MACROPHAGE COLONY-STIMULATING FACTOR).
Entry Version: MCSF
Entry Term(s): CSF-1; CSF-M; Colony-Stimulating Factor 1; Colony-Stimulating Factor, Macrophage; M-CSF
CAS Type 1 Name: Colony-stimulating factor 1
Previous Indexing: Colony-Stimulating Factors (1976-1990)
See Also: Receptor, Macrophage Colony-Stimulating Factor
Public MeSH Note: 91
History Note: 91
Date Established: 1991/01/01
Date of Entry: 1990/06/19
Revision Date: 2023/03/16

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0024689
Scope Note: A mononuclear phagocyte colony-stimulating factor (M-CSF) synthesized by mesenchymal cells. The compound stimulates the survival, proliferation, and differentiation of hematopoietic cells of the monocyte-macrophage series. M-CSF is a disulfide-bonded glycoprotein dimer with a MW of 70 kDa. It binds to a specific high affinity receptor (RECEPTOR, MACROPHAGE COLONY-STIMULATING FACTOR).
Terms: Macrophage Colony-Stimulating Factor Preferred Term
Term UI T048025
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1991); Colony-Stimulating Factor 1
Term UI T048020
Date02/13/1990
LexicalTag NON
ThesaurusID NLM (1991); CSF-1
Term UI T048021
Date02/13/1990
LexicalTag ABB
ThesaurusID NLM (1991); CSF-M
Term UI T048022
Date03/17/1990
LexicalTag ABB
ThesaurusID NLM (1991); M-CSF
Term UI T048023
Date02/13/1990
LexicalTag ABB
ThesaurusID NLM (1991); Colony-Stimulating Factor, Macrophage
Term UI T048024
Date02/13/1990
LexicalTag NON
ThesaurusID NLM (1991)

Macrophage Colony-Stimulating Factor MeSH Descriptor Data 2025