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HIV Long Terminal Repeat MeSH Descriptor Data 2025


MeSH Heading
HIV Long Terminal Repeat
Tree Number(s)
G02.111.570.080.708.850.400
G05.360.080.708.850.400
Unique ID
D016325
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D016325
Scope Note
Regulatory sequences important for viral replication that are located on each end of the HIV genome. The LTR includes the HIV ENHANCER, promoter, and other sequences. Specific regions in the LTR include the negative regulatory element (NRE), NF-kappa B binding sites , Sp1 binding sites, TATA BOX, and trans-acting responsive element (TAR). The binding of both cellular and viral proteins to these regions regulates HIV transcription.
Entry Version
HIV LTR
Entry Term(s)
HIV Negative Regulatory Element
HIV Sp1-Binding Site
HIV Trans-Acting Responsive Region
HIV-1 LTR
Human Immunodeficiency Virus LTR
Human Immunodeficiency Virus Long Terminal Repeat
LTR, Human Immunodeficiency Virus
Long Terminal Repeat, HIV
Negative Regulatory Element, HIV
Sp1-Binding Site, HIV
TAR Element, HIV
Trans-Acting Responsive Region, HIV
Trans-Activation Responsive Element, HIV
Trans-Activation Responsive Region, HIV
Previous Indexing
Repetitive Sequences, Nucleic Acid (1986-1990)
See Also
Gene Products, nef
Gene Products, tat
HIV Enhancer
Sp1 Transcription Factor
Public MeSH Note
91
History Note
91
Date Established
1991/01/01
Date of Entry
1990/06/28
Revision Date
2008/07/08
HIV Long Terminal Repeat Preferred
Negative Regulatory Element, HIV Narrower
Sp1-Binding Site, HIV Narrower
Trans-Acting Responsive Region, HIV Narrower
HIV-1 LTR Narrower
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