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Mitomycin MeSH Descriptor Data 2023


MeSH Heading
Mitomycin
Tree Number(s)
D02.806.400.249.350
D03.383.097.500.350
D03.633.100.473.412.249.350
Unique ID
D016685
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D016685
Annotation
MITOMYCINS is also available
Scope Note
An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
Entry Term(s)
Ametycine
Mitocin-C
Mitomycin C
Mitomycin-C
Mutamycin
NSC-26980
Pharm Action
Alkylating Agents
Antibiotics, Antineoplastic
Cross-Linking Reagents
Nucleic Acid Synthesis Inhibitors
Registry Number
50SG953SK6
Related Numbers
50-07-7
69515-74-8
CAS Type 1 Name
Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione, 6-amino-8-(((aminocarbonyl)oxy)methyl)-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl-, (1aS-(1aalpha,8beta,8aalpha,8balpha))-
Previous Indexing
Mitomycins (1966-1991)
Public MeSH Note
2000; see MITOMYCIN C 1992-1999; MITOMYCIN C was indexed under MITOMYCINS 1981-1990
History Note
2000(1992); for MITOMYCIN use MITOMYCIN (NM) 1981-1991
Entry Combination
analogs & derivatives:Mitomycins
Date Established
1992/01/01
Date of Entry
1991/01/25
Revision Date
2019/07/01
Mitomycin Preferred
Mitocin-C Narrower
NSC-26980 Narrower
Ametycine Narrower
Mutamycin Narrower
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