MeSH Browser

MeSH Heading: Pravastatin
Tree Number(s): D02.455.426.559.847.638.930; D04.615.638.930
Unique ID: D017035
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D017035
Scope Note: An antilipemic fungal metabolite isolated from cultures of Nocardia autotrophica. It acts as a competitive inhibitor of HMG CoA reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES).
Entry Term(s): Apo-Pravastatin; Bristacol; CS-514; Elisor; Eptastatin; Lin-Pravastatin; Lipemol; Liplat; Lipostat; Mevalotin; Nu-Pravastatin; Prareduct; Pravachol; Pravacol; Pravasin; Pravastatin Monosodium Salt, (6 beta)-Isomer; Pravastatin Sodium; Pravastatin Sodium Salt; Pravastatin tert-Octylamine Salt; Pravastatin, (6 beta)-Isomer; RMS-431; SQ-31,000; SQ-31000; Selektine; Vasten
Pharm Action: Anticholesteremic Agents
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Related Numbers: 124917-23-3; 3M8608UQ61; 81093-37-0; 81131-70-6; 81131-74-0; 81176-41-2
CAS Type 1 Name: 1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-beta,delta,6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-, (1S-(1alpha(betaS*,deltaS*),2alpha,6alpha,8beta(R*),8aalpha))-
Public MeSH Note: 92; PRAVASTATIN was indexed under NAPHTHALENES & HEPTANOIC ACIDS 1986-91
Online Note: use PRAVASTATIN (NM) to search PRAVASTATIN 1986-91
History Note: 92; was PRAVASTATIN (NM) 1986-91
Date Established: 1992/01/01
Date of Entry: 1991/07/12
Revision Date: 2016/07/01

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Organic Chemicals [D02]
- Hydrocarbons [D02.455]
  - Hydrocarbons, Cyclic [D02.455.426]
    - Hydrocarbons, Aromatic [D02.455.426.559]
      - Polycyclic Aromatic Hydrocarbons [D02.455.426.559.847]
        
        Naphthalenes [D02.455.426.559.847.638]
        
        Acenaphthenes [D02.455.426.559.847.638.059]
        
        Adapalene [D02.455.426.559.847.638.090]
        
        Bunaftine [D02.455.426.559.847.638.120]
        
        Carbaryl [D02.455.426.559.847.638.162]
        
        Cinacalcet [D02.455.426.559.847.638.183]
        
        Dansyl Compounds [D02.455.426.559.847.638.204]
        
        Lovastatin [D02.455.426.559.847.638.400]
        
        Naphthaleneacetic Acids [D02.455.426.559.847.638.472]
        
        Naphthalenesulfonates [D02.455.426.559.847.638.555]
        
        Naphthols [D02.455.426.559.847.638.638]
        
        Naphthoquinones [D02.455.426.559.847.638.721]
        
        1-Naphthylamine [D02.455.426.559.847.638.845]
        
        2-Naphthylamine [D02.455.426.559.847.638.850]
        
        1-Naphthylisothiocyanate [D02.455.426.559.847.638.870]
        
        Naphthylvinylpyridine [D02.455.426.559.847.638.900]
        
        Pravastatin [D02.455.426.559.847.638.930]
        
        Propranolol [D02.455.426.559.847.638.945]
        
        Terbinafine [D02.455.426.559.847.638.953]
        
        Tetrahydronaphthalenes [D02.455.426.559.847.638.960]
        
        Tolnaftate [D02.455.426.559.847.638.975]

Polycyclic Compounds [D04]
- Polycyclic Aromatic Hydrocarbons [D04.615]
  - Naphthalenes [D04.615.638]

Pravastatin Preferred

SQ-31000 Narrower

Pravastatin tert-Octylamine Salt Narrower

Pravastatin Sodium Narrower

Pravastatin, (6 beta)-Isomer Narrower

Pravastatin Monosodium Salt, (6 beta)-Isomer Narrower

CS-514 Narrower

Pravachol Narrower

Concept UI: M0350932
Terms: Pravachol Preferred Term
Term UI T050849
Date04/05/1991
LexicalTag TRD
ThesaurusID; Pravacol
Term UI T617924
Date11/11/2004
LexicalTag TRD
ThesaurusID MX; Pravasin
Term UI T617925
Date11/11/2004
LexicalTag TRD
ThesaurusID DE; Selektine
Term UI T617926
Date11/11/2004
LexicalTag TRD
ThesaurusID NL; Lipostat
Term UI T617928
Date11/11/2004
LexicalTag TRD
ThesaurusID; Elisor
Term UI T617929
Date11/11/2004
LexicalTag TRD
ThesaurusID FR

RMS-431 Narrower

Apo-Pravastatin Narrower

Bristacol Narrower

Prareduct Narrower

Lin-Pravastatin Narrower

Lipemol Narrower

Liplat Narrower

Vasten Narrower

Nu-Pravastatin Narrower

Pravastatin MeSH Descriptor Data 2025