- Concept UI
- M0012707
- Registry Numbers
- 9LHU78OQFD
- Related Numbers
- 75330-75-5
- 79902-41-3
- 79952-44-6
- Scope Note
- A fungal metabolite isolated from cultures of Aspergillus terreus. The compound is a potent anticholesteremic agent. It inhibits 3-hydroxy-3-methylglutaryl coenzyme A reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES), which is the rate-limiting enzyme in cholesterol biosynthesis. It also stimulates the production of low-density lipoprotein receptors in the liver.
- Terms
-
Lovastatin
Preferred Term
Term UI
T024290
Date01/01/1999
LexicalTag
NON
ThesaurusID
-
6-Methylcompactin
Term UI
T024289
Date05/04/1987
LexicalTag
NON
ThesaurusID
UNK (19XX)
-
Mevinolin
Term UI
T024292
Date05/04/1987
LexicalTag
NON
ThesaurusID
-
Monacolin K
Term UI
T024294
Date10/27/1997
LexicalTag
NON
ThesaurusID