MeSH Browser

MeSH Heading: Mice, Inbred mdx
Tree Number(s): B01.050.050.199.520.520.420.500; B01.050.150.900.649.313.992.635.505.500.400.420.500; B01.050.150.900.649.313.992.635.505.500.550.265
Unique ID: D018101
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D018101
Annotation: NIM with no qualifiers when experimental animal
Scope Note: A strain of mice arising from a spontaneous MUTATION (mdx) in inbred C57BL mice. This mutation is X chromosome-linked and produces viable homozygous animals that lack the muscle protein DYSTROPHIN, have high serum levels of muscle ENZYMES, and possess histological lesions similar to human MUSCULAR DYSTROPHY. The histological features, linkage, and map position of mdx make these mice a worthy animal model of DUCHENNE MUSCULAR DYSTROPHY.
Entry Term(s): Mice, mdx; Mouse, Inbred mdx; Mouse, mdx
Previous Indexing: Mice, Inbred C57BL (1984-1993); Mice, Mutant Strains (1984-1993)
See Also: Muscular Dystrophies
Public MeSH Note: 94
History Note: 94
Date Established: 1994/01/01
Date of Entry: 1993/06/03
Revision Date: 2020/09/02

Allowable Qualifiers: abnormalities (AB)

anatomy & histology (AH)

blood (BL)

cerebrospinal fluid (CF)

classification (CL)

embryology (EM)

genetics (GE)

growth & development (GD)

immunology (IM)

injuries (IN)

metabolism (ME)

microbiology (MI)

parasitology (PS)

physiology (PH)

psychology (PX)

surgery (SU)

urine (UR)

virology (VI)

Concept UI: M0027297
Scope Note: A strain of mice arising from a spontaneous MUTATION (mdx) in inbred C57BL mice. This mutation is X chromosome-linked and produces viable homozygous animals that lack the muscle protein DYSTROPHIN, have high serum levels of muscle ENZYMES, and possess histological lesions similar to human MUSCULAR DYSTROPHY. The histological features, linkage, and map position of mdx make these mice a worthy animal model of DUCHENNE MUSCULAR DYSTROPHY.
Terms: Mice, Inbred mdx Preferred Term
Term UI T054159
Date01/01/1999
LexicalTag ACX
ThesaurusID NLM (1994); Mice, mdx
Term UI T054156
Date03/08/1993
LexicalTag NON
ThesaurusID NLM (1994); Mouse, mdx
Term UI T054157
Date03/08/1993
LexicalTag NON
ThesaurusID NLM (1994); Mouse, Inbred mdx
Term UI T054158
Date02/04/1993
LexicalTag NON
ThesaurusID NLM (1994)

Mice, Inbred mdx MeSH Descriptor Data 2025