MeSH Browser

MeSH Heading: Muscular Dystrophy, Duchenne
Tree Number(s): C05.651.534.500.300; C10.668.491.175.500.300; C16.320.322.562; C16.320.577.300
Unique ID: D020388
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D020388
Scope Note: An X-linked recessive muscle disease caused by an inability to synthesize DYSTROPHIN, which is involved with maintaining the integrity of the sarcolemma. Muscle fibers undergo a process that features degeneration and regeneration. Clinical manifestations include proximal weakness in the first few years of life, pseudohypertrophy, cardiomyopathy (see MYOCARDIAL DISEASES), and an increased incidence of impaired mentation. Becker muscular dystrophy is a closely related condition featuring a later onset of disease (usually adolescence) and a slowly progressive course. (Adams et al., Principles of Neurology, 6th ed, p1415)
Entry Term(s): Becker Muscular Dystrophy; Becker's Muscular Dystrophy; Cardiomyopathy, Dilated, 3B; Cardiomyopathy, Dilated, X-Linked; Childhood Muscular Dystrophy, Pseudohypertrophic; Childhood Pseudohypertrophic Muscular Dystrophy; Duchenne Muscular Dystrophy; Duchenne and Becker Muscular Dystrophy; Duchenne-Becker Muscular Dystrophy; Duchenne-Type Progressive Muscular Dystrophy; Muscular Dystrophy Pseudohypertrophic Progressive, Becker Type; Muscular Dystrophy, Becker; Muscular Dystrophy, Becker Type; Muscular Dystrophy, Childhood, Pseudohypertrophic; Muscular Dystrophy, Duchenne Type; Muscular Dystrophy, Duchenne and Becker Types; Muscular Dystrophy, Pseudohypertrophic; Muscular Dystrophy, Pseudohypertrophic Progressive, Becker Type; Muscular Dystrophy, Pseudohypertrophic Progressive, Duchenne Type; Muscular Dystrophy, Pseudohypertrophic, Childhood; Progressive Muscular Dystrophy, Duchenne Type; Pseudohypertrophic Childhood Muscular Dystrophy; Pseudohypertrophic Muscular Dystrophy, Childhood
Previous Indexing: Muscular Dystrophies (1966-1999)
See Also: Dystrophin
Public MeSH Note: 2000; see MUSCULAR DYSTROPHIES 1980-1999; for MUSCULAR DYSTROPHY, BECKER & BECKER MUSCULAR DYSTROPHY see MUSCULAR DYSTROPHIES 1991-1999
History Note: 2000; use MUSCULAR DYSTROPHIES 1980-1999; for MUSCULAR DYSTROPHY, BECKER & BECKER MUSCULAR DYSTROPHY use MUSCULAR DYSTROPHIES 1991-1999
Date Established: 2000/01/01
Date of Entry: 1999/11/08
Revision Date: 2013/07/08

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

congenital (CN)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

virology (VI)

Musculoskeletal Diseases [C05]
- Muscular Diseases [C05.651]
  - Muscular Disorders, Atrophic [C05.651.534]
    - Muscular Dystrophies [C05.651.534.500]

Nervous System Diseases [C10]
- Neuromuscular Diseases [C10.668]
  - Muscular Diseases [C10.668.491]
    - Muscular Disorders, Atrophic [C10.668.491.175]
      - Muscular Dystrophies [C10.668.491.175.500]
        
        Distal Myopathies [C10.668.491.175.500.074]
        
        Glycogen Storage Disease Type VII [C10.668.491.175.500.112]
        
        Muscular Dystrophies, Limb-Girdle [C10.668.491.175.500.149]
        
        Muscular Dystrophy, Duchenne [C10.668.491.175.500.300]
        
        Muscular Dystrophy, Emery-Dreifuss [C10.668.491.175.500.350]
        
        Muscular Dystrophy, Facioscapulohumeral [C10.668.491.175.500.400]
        
        Muscular Dystrophy, Oculopharyngeal [C10.668.491.175.500.450]
        
        Myotonic Dystrophy [C10.668.491.175.500.500]

Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
- Genetic Diseases, Inborn [C16.320]
  - Genetic Diseases, X-Linked [C16.320.322]

Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
- Genetic Diseases, Inborn [C16.320]
  - Muscular Dystrophies [C16.320.577]

Muscular Dystrophy, Duchenne Preferred

Becker Muscular Dystrophy Related

Duchenne and Becker Muscular Dystrophy Broader

Muscular Dystrophy, Duchenne MeSH Descriptor Data 2025