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Genes, erbB-2 MeSH Descriptor Data 2023


MeSH Heading
Genes, erbB-2
Tree Number(s)
G05.360.340.024.340.375.500.791.295.305
Unique ID
D018734
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D018734
Annotation
in titles & translations spell as erbB-2; GENES, ERBB-1 is also available
Scope Note
The erbB-2 gene is a proto-oncogene that codes for the erbB-2 receptor (RECEPTOR, ERBB-2), a protein with structural features similar to the epidermal growth factor receptor. Its name originates from the viral oncogene homolog (v-erbB) which is a truncated form of the chicken erbB gene found in the avian erythroblastosis virus. Overexpression and amplification of the gene is associated with a significant number of adenocarcinomas. The human c-erbB-2 gene is located at 17q21.2.
Entry Term(s)
Genes, HER-2
Genes, HER2
Genes, erbb2
Genes, neu
c-erbB-2 Genes
c-erbB-2 Proto-Oncogenes
erbB-2 Genes
Previous Indexing
Oncogenes (1986-1994)
Proto-Oncogenes (1986-1994)
See Also
ErbB Receptors
Oncogene Proteins v-erbB
Receptor, ErbB-2
Public MeSH Note
1995
History Note
1995
Date Established
1995/01/01
Date of Entry
1994/05/23
Revision Date
2018/06/12
Genes, erbB-2 Preferred
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