MeSH Browser

MeSH Heading: Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Tree Number(s): E05.196.566.755
Unique ID: D019032
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D019032
Scope Note: A mass spectrometric technique that is used for the analysis of large biomolecules. Analyte molecules are embedded in an excess matrix of small organic molecules that show a high resonant absorption at the laser wavelength used. The matrix absorbs the laser energy, thus inducing a soft disintegration of the sample-matrix mixture into free (gas phase) matrix and analyte molecules and molecular ions. In general, only molecular ions of the analyte molecules are produced, and almost no fragmentation occurs. This makes the method well suited for molecular weight determinations and mixture analysis.
Entry Term(s): Laser Desorption-Ionization Mass Spectrometry, Matrix-Assisted; MALD-MS; MALDI; MALDI-MS; MS-MALD; Mass Spectrometry, Matrix-Assisted Laser Desorption-Ionization; Mass Spectroscopy, Matrix-Assisted Laser Desorption-Ionization; Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry; SELDI-TOF-MS; Spectroscopy, Mass, Matrix-Assisted Laser Desorption-Ionization; Surface Enhanced Laser Desorption Ionization Mass Spectrometry
Previous Indexing: Spectrum Analysis, Mass (1989-1995)
Public MeSH Note: 96
History Note: 96
Date Established: 1996/01/01
Date of Entry: 1995/05/26
Revision Date: 2006/07/05

Allowable Qualifiers: classification (CL)

economics (EC)

ethics (ES)

history (HI)

instrumentation (IS)

methods (MT)

standards (ST)

statistics & numerical data (SN)

trends (TD)

veterinary (VE)

Investigative Techniques [E05]
- Chemistry Techniques, Analytical [E05.196]
  - Mass Spectrometry [E05.196.566]

Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Preferred

Concept UI: M0028408
Scope Note: A mass spectrometric technique that is used for the analysis of large biomolecules. Analyte molecules are embedded in an excess matrix of small organic molecules that show a high resonant absorption at the laser wavelength used. The matrix absorbs the laser energy, thus inducing a soft disintegration of the sample-matrix mixture into free (gas phase) matrix and analyte molecules and molecular ions. In general, only molecular ions of the analyte molecules are produced, and almost no fragmentation occurs. This makes the method well suited for molecular weight determinations and mixture analysis.
Terms: Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Preferred Term
Term UI T056782
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1996); Mass Spectrometry, Matrix-Assisted Laser Desorption-Ionization
Term UI T056780
Date01/19/1995
LexicalTag NON
ThesaurusID NLM (1996); Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry
Term UI T056781
Date01/19/1995
LexicalTag NON
ThesaurusID NLM (1996); Mass Spectroscopy, Matrix-Assisted Laser Desorption-Ionization
Term UI T056783
Date01/19/1995
LexicalTag NON
ThesaurusID NLM (1996); Spectroscopy, Mass, Matrix-Assisted Laser Desorption-Ionization
Term UI T056784
Date01/19/1995
LexicalTag NON
ThesaurusID NLM (1996); MS-MALD
Term UI T056785
Date03/22/1995
LexicalTag ABB
ThesaurusID NLM (1996); MALD-MS
Term UI T056786
Date01/19/1995
LexicalTag ABB
ThesaurusID NLM (1996); MALDI-MS
Term UI T461420
Date09/13/2001
LexicalTag NON
ThesaurusID NLM (2003); Laser Desorption-Ionization Mass Spectrometry, Matrix-Assisted
Term UI T056779
Date05/25/1995
LexicalTag NON
ThesaurusID NLM (1996); MALDI
Term UI T461421
Date09/13/2001
LexicalTag NON
ThesaurusID NLM (2003)

Surface Enhanced Laser Desorption Ionization Mass Spectrometry Narrower

Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization MeSH Descriptor Data 2025