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Spectrometry, Mass, Electrospray Ionization MeSH Descriptor Data 2025


MeSH Heading
Spectrometry, Mass, Electrospray Ionization
Tree Number(s)
E05.196.566.600
Unique ID
D021241
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D021241
Scope Note
A mass spectrometry technique used for analysis of nonvolatile compounds such as proteins and macromolecules. The technique involves preparing electrically charged droplets from analyte molecules dissolved in solvent. The electrically charged droplets enter a vacuum chamber where the solvent is evaporated. Evaporation of solvent reduces the droplet size, thereby increasing the coulombic repulsion within the droplet. As the charged droplets get smaller, the excess charge within them causes them to disintegrate and release analyte molecules. The volatilized analyte molecules are then analyzed by mass spectrometry.
Entry Term(s)
ESI Mass Spectrometry
Electrospray Ionization Mass Spectrometry
Previous Indexing
Spectrum Analysis, Mass (1985-2000)
Public MeSH Note
2001
History Note
2001
Date Established
2001/01/01
Date of Entry
2000/06/22
Revision Date
2006/07/05
Spectrometry, Mass, Electrospray Ionization Preferred
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