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Cromakalim MeSH Descriptor Data 2023


MeSH Heading
Cromakalim
Tree Number(s)
D03.383.129.578.150
D03.383.663.283.455
D03.633.100.150.455
Unique ID
D019806
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D019806
Scope Note
A potassium-channel opening vasodilator that has been investigated in the management of hypertension. It has also been tried in patients with asthma. (Martindale, The Extra Pharmacopoeia, 30th ed, p352)
Entry Term(s)
BRL-34915
BRL-38226
BRL-38227
Cromakalim, (3R-cis)-Isomer
Cromakalim, (3R-trans)-Isomer
Cromakalim, (3S-cis)-Isomer
Cromakalim, (3S-trans)-Isomer
Cromakalim, (trans)-Isomer
Lemakalim
Levcromakalim
Pharm Action
Antihypertensive Agents
Bronchodilator Agents
Parasympatholytics
Vasodilator Agents
Registry Number
0G4X367WA3
Related Numbers
148811-93-2
148811-94-3
150871-62-8
86776-67-2
94470-67-4
94535-50-9
94535-51-0
RW7PN4BLDJ
CAS Type 1 Name
2H-1-Benzopyran-6-carbonitrile, 3,4-dihydro-3-hydroxy-2,2-dimethyl-4-(2-oxo-1-pyrrolidinyl)-, trans-(+-)-
Previous Indexing
Benzopyrans (1986-1997)
Pyrroles (1986-1997)
Public MeSH Note
98; CROMAKALIM was indexed under BENZOPYRANS & PYRROLES 1986-97
History Note
98; use CROMAKALIM (NM) 1986-97
Date Established
1998/01/01
Date of Entry
1997/06/20
Revision Date
2016/05/28
Cromakalim Preferred
BRL-34915 Narrower
BRL-38226 Narrower
Cromakalim, (3R-cis)-Isomer Narrower
Cromakalim, (3S-cis)-Isomer Narrower
Cromakalim, (trans)-Isomer Narrower
Lemakalim Narrower
Levcromakalim Narrower
BRL-38227 Narrower
Cromakalim, (3R-trans)-Isomer Narrower
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