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Duocarmycins MeSH Descriptor Data 2023


MeSH Heading
Duocarmycins
Tree Number(s)
D03.383.129.578.275
D03.633.100.473.278
Unique ID
D000080890
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000080890
Scope Note
A group of pyrroloindole compounds often with additional spirocyclic unit(s) and their analogs originally isolated from STREPTOMYCES. They bind DNA minor grooves with adenine-N3 alkylation activity.
Entry Term(s)
Duocarmycin
Pharm Action
Antibiotics, Antineoplastic
Antineoplastic Agents, Alkylating
Registry Number
0
Previous Indexing
Indoles (1988-2019)
Pyrroles (1988-2019)
Public MeSH Note
2020
History Note
2020
Date Established
2020/01/01
Date of Entry
2019/07/08
Revision Date
2019/05/17
Duocarmycins Preferred
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