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Indomethacin
MeSH Descriptor Data 2025
Details
Qualifiers
MeSH Tree Structures
Concepts
MeSH Heading
Indomethacin
Tree Number(s)
D03.633.100.473.420
Unique ID
D007213
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D007213
Scope Note
A non-steroidal anti-inflammatory agent (
NSAID
) that inhibits
CYCLOOXYGENASE
, which is necessary for the formation of
PROSTAGLANDINS
and other
AUTACOIDS
. It also inhibits the motility of
POLYMORPHONUCLEAR LEUKOCYTES
.
Entry Term(s)
Amuno
Indocid
Indocin
Indomet 140
Indometacin
Indomethacin Hydrochloride
Metindol
Osmosin
Pharm Action
Anti-Inflammatory Agents, Non-Steroidal
Cardiovascular Agents
Gout Suppressants
Tocolytic Agents
Cyclooxygenase Inhibitors
Related Numbers
104614-77-9
113560-66-0
125770-88-9
28811-31-6
28811-32-7
53-86-1
58201-41-5
62509-41-5
70938-94-2
74252-25-8
7681-54-1
86947-68-4
88170-06-3
CAS Type 1 Name
1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-
NLM Classification #
QV 95
Public MeSH Note
1966
History Note
1966 (1964)
Date Established
1966/01/01
Date of Entry
1999/01/01
Revision Date
2018/04/10
Allowable Qualifiers
administration & dosage (AD)
adverse effects (AE)
agonists (AG)
analogs & derivatives (AA)
analysis (AN)
antagonists & inhibitors (AI)
blood (BL)
cerebrospinal fluid (CF)
chemical synthesis (CS)
chemistry (CH)
classification (CL)
economics (EC)
history (HI)
immunology (IM)
isolation & purification (IP)
metabolism (ME)
pharmacokinetics (PK)
pharmacology (PD)
poisoning (PO)
radiation effects (RE)
standards (ST)
supply & distribution (SD)
therapeutic use (TU)
toxicity (TO)
urine (UR)
Heterocyclic Compounds [D03]
Heterocyclic Compounds, Fused-Ring [D03.633]
Heterocyclic Compounds, 2-Ring [D03.633.100]
Indoles [D03.633.100.473]
Adrenochrome [D03.633.100.473.025]
Alcian Blue [D03.633.100.473.050]
Carbazoles [D03.633.100.473.144]
Cytochalasins [D03.633.100.473.231]
Delavirdine [D03.633.100.473.250]
Duocarmycins [D03.633.100.473.278]
Fluvastatin [D03.633.100.473.305]
Gliotoxin [D03.633.100.473.360]
Hydroxytryptophol [D03.633.100.473.385]
Ibogaine [D03.633.100.473.390]
Indapamide [D03.633.100.473.391]
Indican [D03.633.100.473.393]
Indigo Carmine [D03.633.100.473.396]
Indocyanine Green [D03.633.100.473.400]
Indole Alkaloids [D03.633.100.473.402]
Indoleacetic Acids [D03.633.100.473.404]
Indolequinones [D03.633.100.473.412]
Indolosesquiterpenes [D03.633.100.473.416]
Indomethacin [D03.633.100.473.420]
Ketorolac [D03.633.100.473.420.485]
Ketorolac Tromethamine [D03.633.100.473.420.742]
Indoramin [D03.633.100.473.432]
Iprindole [D03.633.100.473.469]
Isatin [D03.633.100.473.525]
Methisazone [D03.633.100.473.615]
Molindone [D03.633.100.473.629]
Oxyphenisatin Acetate [D03.633.100.473.725]
Panobinostat [D03.633.100.473.746]
Perindopril [D03.633.100.473.766]
Skatole [D03.633.100.473.808]
Sporidesmins [D03.633.100.473.840]
Sunitinib [D03.633.100.473.877]
Tropisetron [D03.633.100.473.896]
Tryptamines [D03.633.100.473.914]
Vemurafenib [D03.633.100.473.936]
Vilazodone Hydrochloride [D03.633.100.473.957]
Expand All
Collapse All
Indomethacin
Preferred
Concept UI
M0011240
Related Numbers
104614-77-9
113560-66-0
125770-88-9
28811-31-6
28811-32-7
53-86-1
58201-41-5
62509-41-5
70938-94-2
74252-25-8
7681-54-1
86947-68-4
88170-06-3
Scope Note
A non-steroidal anti-inflammatory agent (
NSAID
) that inhibits
CYCLOOXYGENASE
, which is necessary for the formation of
PROSTAGLANDINS
and other
AUTACOIDS
. It also inhibits the motility of
POLYMORPHONUCLEAR LEUKOCYTES
.
Terms
Indomethacin
Preferred Term
Term UI
T021616
Date
01/01/1999
LexicalTag
NON
ThesaurusID
Indometacin
Term UI
T021619
Date
11/29/1996
LexicalTag
NON
ThesaurusID
Osmosin
Narrower
Concept UI
M0011241
Terms
Osmosin
Preferred Term
Term UI
T021620
Date
09/14/1983
LexicalTag
TRD
ThesaurusID
UNK (19XX)
Indocid
Narrower
Concept UI
M0011242
Terms
Indocid
Preferred Term
Term UI
T021621
Date
10/26/1981
LexicalTag
TRD
ThesaurusID
UNK (19XX)
Indomethacin Hydrochloride
Narrower
Concept UI
M0330169
Terms
Indomethacin Hydrochloride
Preferred Term
Term UI
T360363
Date
09/13/1999
LexicalTag
NON
ThesaurusID
NLM (1999)
Amuno
Narrower
Concept UI
M0353728
Terms
Amuno
Preferred Term
Term UI
T021613
Date
09/16/1983
LexicalTag
TRD
ThesaurusID
UNK (19XX)
Indocin
Narrower
Concept UI
M0353731
Terms
Indocin
Preferred Term
Term UI
T021614
Date
12/09/1983
LexicalTag
TRD
ThesaurusID
UNK (19XX)
Metindol
Narrower
Concept UI
M0353732
Terms
Metindol
Preferred Term
Term UI
T021617
Date
08/01/1980
LexicalTag
TRD
ThesaurusID
UNK (19XX)
Indomet 140
Narrower
Concept UI
M0353733
Terms
Indomet 140
Preferred Term
Term UI
T021615
Date
11/29/1982
LexicalTag
TRD
ThesaurusID
UNK (19XX)
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