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Panobinostat MeSH Descriptor Data 2023


MeSH Heading
Panobinostat
Tree Number(s)
D02.092.570.394.535
D02.241.511.372.535
D03.633.100.473.746
Unique ID
D000077767
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000077767
Scope Note
An indole and hydroxamic acid derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used as an antineoplastic agent in combination with BORTEZOMIB and DEXAMETHASONE for the treatment of MULTIPLE MYELOMA.
Entry Term(s)
Farydak
LBH 589
LBH589
NVP-LBH589
Pharm Action
Antineoplastic Agents
Histone Deacetylase Inhibitors
Registry Number
9647FM7Y3Z
CAS Type 1 Name
2-Propenamide, N-hydroxy-3-(4-(((2-(2-methyl-1H-indol-3-yl)ethyl)amino) methyl)phenyl)-, (2E)-
Public MeSH Note
2019; PANOBINOSTAT was indexed under HYDROXAMIC ACIDS and INDOLES 2005-2018
History Note
2019 (2005)
Date Established
2019/01/01
Date of Entry
2018/07/09
Revision Date
2018/05/21
Panobinostat Preferred
LBH589 Narrower
Farydak Narrower
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