MeSH Browser

MeSH Heading: Choline-Phosphate Cytidylyltransferase
Tree Number(s): D08.811.913.696.445.184
Unique ID: D019916
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D019916
Scope Note: An enzyme that catalyzes the transfer of cytidylate (CMP) to choline phosphate to form CDPcholine. It is the rate-limiting enzyme in the choline pathway for the biosynthesis of phosphatidylcholine. Its activity is increased by glucocorticoids. EC 2.7.7.15.
Entry Term(s): CDP-Choline Synthetase; CTP Phosphocholine Cytidylyl-Transferase; CTP Phosphocholine Cytidylyltransferase; CTP Phosphorylcholine Cytidyltransferase; Phosphocholine Cytidyltransferase; Phosphorylcholine Cytidyl Transferase
Registry Numbers: EC 2.7.7.15
Related Numbers: 9026-34-0
Previous Indexing: Choline (1975-1977); Cytidine Diphosphate Choline (1977-1981); Cytosine Nucleotides (1975-1977); Nucleotidyltransferases (1975-1997)
Public MeSH Note: 98; CHOLINE-PHOSPHATE CYTIDYLTRANSFERASE was indexed under CYTOSINE NUCLEOTIDES & CHOLINE 1975-77, CYTIDINE DIPHOSPHATE CHOLINE 1977-81 & NUCLEOTIDYLTRANSFERASES 1975-97
History Note: 98; use CHOLINE-PHOSPHATE CYTIDYLYLTRANSFERASE (NM) 1980-97
Date Established: 1998/01/01
Date of Entry: 1997/06/20
Revision Date: 2006/07/05

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0029591
Registry Numbers: EC 2.7.7.15
Related Numbers: 9026-34-0
Scope Note: An enzyme that catalyzes the transfer of cytidylate (CMP) to choline phosphate to form CDPcholine. It is the rate-limiting enzyme in the choline pathway for the biosynthesis of phosphatidylcholine. Its activity is increased by glucocorticoids. EC 2.7.7.15.
Terms: Choline-Phosphate Cytidylyltransferase Preferred Term
Term UI T059353
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1998); CDP-Choline Synthetase
Term UI T059347
Date02/24/1997
LexicalTag NON
ThesaurusID NLM (1998); CTP Phosphocholine Cytidylyl-Transferase
Term UI T059352
Date02/24/1997
LexicalTag NON
ThesaurusID NLM (1998); CTP Phosphocholine Cytidylyltransferase
Term UI T059348
Date02/24/1997
LexicalTag NON
ThesaurusID NLM (1998); CTP Phosphorylcholine Cytidyltransferase
Term UI T059349
Date02/24/1997
LexicalTag NON
ThesaurusID NLM (1998); Phosphocholine Cytidyltransferase
Term UI T059350
Date02/24/1997
LexicalTag NON
ThesaurusID NLM (1998); Phosphorylcholine Cytidyl Transferase
Term UI T059351
Date02/24/1997
LexicalTag NON
ThesaurusID NLM (1998)

Choline-Phosphate Cytidylyltransferase MeSH Descriptor Data 2024