rab5 GTP-Binding Proteins MeSH Descriptor Data 2025

MeSH Heading: rab5 GTP-Binding Proteins
Tree Number(s): D08.811.277.040.330.300.400.400.200; D12.776.157.325.515.400.200; D12.776.476.338.400.400.200
Unique ID: D020696
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D020696
Scope Note: A genetically related subfamily of RAB GTP-BINDING PROTEINS involved in transport from the cell membrane to early endosomes. This enzyme was formerly listed as EC 3.6.1.47.
Entry Term(s): rab5 GTP-Binding Protein; rab5 Protein; rab5A GTP-Binding Protein; rab5A Protein
Previous Indexing: G-Proteins (1992-1999)
Public MeSH Note: 2000; RAB5 PROTEIN (now RAB5 GTP-BINDING PROTEINS) was indexed under G-PROTEINS 1991-1999
History Note: 2000; use RAB5 GTP-BINDING PROTEINS (NM) 1991-1999
Date Established: 2000/01/01
Date of Entry: 1999/11/03
Revision Date: 2021/05/21

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Acid Anhydride Hydrolases [D08.811.277.040]
      - GTP Phosphohydrolases [D08.811.277.040.330]
        
        GTP-Binding Proteins [D08.811.277.040.330.300]
        
        Monomeric GTP-Binding Proteins [D08.811.277.040.330.300.400]
        
        rab GTP-Binding Proteins [D08.811.277.040.330.300.400.400]
        
        rab1 GTP-Binding Proteins [D08.811.277.040.330.300.400.400.025]
        
        rab2 GTP-Binding Protein [D08.811.277.040.330.300.400.400.050]
        
        rab27 GTP-Binding Proteins [D08.811.277.040.330.300.400.400.075]
        
        rab3 GTP-Binding Proteins [D08.811.277.040.330.300.400.400.100]
        
        rab4 GTP-Binding Proteins [D08.811.277.040.330.300.400.400.150]
        
        rab5 GTP-Binding Proteins [D08.811.277.040.330.300.400.400.200]
        
        rab7 GTP-Binding Proteins [D08.811.277.040.330.300.400.400.600]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Carrier Proteins [D12.776.157]
    - GTP-Binding Proteins [D12.776.157.325]
      - Monomeric GTP-Binding Proteins [D12.776.157.325.515]
        
        rab GTP-Binding Proteins [D12.776.157.325.515.400]
        
        rab1 GTP-Binding Proteins [D12.776.157.325.515.400.025]
        
        rab2 GTP-Binding Protein [D12.776.157.325.515.400.050]
        
        rab27 GTP-Binding Proteins [D12.776.157.325.515.400.075]
        
        rab3 GTP-Binding Proteins [D12.776.157.325.515.400.100]
        
        rab4 GTP-Binding Proteins [D12.776.157.325.515.400.150]
        
        rab5 GTP-Binding Proteins [D12.776.157.325.515.400.200]
        
        rab7 GTP-Binding Proteins [D12.776.157.325.515.400.600]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Intracellular Signaling Peptides and Proteins [D12.776.476]
    - GTP-Binding Proteins [D12.776.476.338]
      - Monomeric GTP-Binding Proteins [D12.776.476.338.400]
        
        rab GTP-Binding Proteins [D12.776.476.338.400.400]
        
        rab1 GTP-Binding Proteins [D12.776.476.338.400.400.025]
        
        rab2 GTP-Binding Protein [D12.776.476.338.400.400.050]
        
        rab27 GTP-Binding Proteins [D12.776.476.338.400.400.075]
        
        rab3 GTP-Binding Proteins [D12.776.476.338.400.400.100]
        
        rab4 GTP-Binding Proteins [D12.776.476.338.400.400.150]
        
        rab5 GTP-Binding Proteins [D12.776.476.338.400.400.200]
        
        rab7 GTP-Binding Proteins [D12.776.476.338.400.400.600]

rab5 GTP-Binding Proteins Preferred

rab5A GTP-Binding Protein Narrower

Concept UI: M0185755
Terms: rab5A GTP-Binding Protein Preferred Term
Term UI T363035
Date10/12/1999
LexicalTag ABX
ThesaurusID NLM (2000); rab5A Protein
Term UI T215760
Date10/12/1999
LexicalTag ABX
ThesaurusID NLM (2000); rab5 Protein
Term UI T215762
Date10/12/1999
LexicalTag ABX
ThesaurusID NLM (2000); rab5 GTP-Binding Protein
Term UI T363036
Date10/12/1999
LexicalTag ABX
ThesaurusID NLM (2000)

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