rab GTP-Binding Proteins MeSH Descriptor Data 2025

MeSH Heading: rab GTP-Binding Proteins
Tree Number(s): D08.811.277.040.330.300.400.400; D12.776.157.325.515.400; D12.776.476.338.400.400
Unique ID: D020691
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D020691
Scope Note: A large family of MONOMERIC GTP-BINDING PROTEINS that play a key role in cellular secretory and endocytic pathways.
Entry Term(s): Rab GTPase; rab G-Proteins; rab GTP-Binding Protein; rab GTPases
Previous Indexing: G-Proteins (1989-1999)
Public MeSH Note: 2000
History Note: 2000
Date Established: 2000/01/01
Date of Entry: 1999/11/04
Revision Date: 2021/05/21

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Acid Anhydride Hydrolases [D08.811.277.040]
      - GTP Phosphohydrolases [D08.811.277.040.330]
        
        GTP-Binding Proteins [D08.811.277.040.330.300]
        
        Monomeric GTP-Binding Proteins [D08.811.277.040.330.300.400]
        
        ADP-Ribosylation Factors [D08.811.277.040.330.300.400.100]
        
        rab GTP-Binding Proteins [D08.811.277.040.330.300.400.400]
        
        rab1 GTP-Binding Proteins [D08.811.277.040.330.300.400.400.025]
        
        rab2 GTP-Binding Protein [D08.811.277.040.330.300.400.400.050]
        
        rab27 GTP-Binding Proteins [D08.811.277.040.330.300.400.400.075]
        
        rab3 GTP-Binding Proteins [D08.811.277.040.330.300.400.400.100]
        
        rab4 GTP-Binding Proteins [D08.811.277.040.330.300.400.400.150]
        
        rab5 GTP-Binding Proteins [D08.811.277.040.330.300.400.400.200]
        
        rab7 GTP-Binding Proteins [D08.811.277.040.330.300.400.400.600]
        
        ral GTP-Binding Proteins [D08.811.277.040.330.300.400.450]
        
        ran GTP-Binding Protein [D08.811.277.040.330.300.400.462]
        
        rap GTP-Binding Proteins [D08.811.277.040.330.300.400.475]
        
        Ras Homolog Enriched in Brain Protein [D08.811.277.040.330.300.400.488]
        
        ras Proteins [D08.811.277.040.330.300.400.500]
        
        rho GTP-Binding Proteins [D08.811.277.040.330.300.400.700]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Carrier Proteins [D12.776.157]
    - GTP-Binding Proteins [D12.776.157.325]
      - Monomeric GTP-Binding Proteins [D12.776.157.325.515]
        
        ADP-Ribosylation Factors [D12.776.157.325.515.100]
        
        rab GTP-Binding Proteins [D12.776.157.325.515.400]
        
        rab1 GTP-Binding Proteins [D12.776.157.325.515.400.025]
        
        rab2 GTP-Binding Protein [D12.776.157.325.515.400.050]
        
        rab27 GTP-Binding Proteins [D12.776.157.325.515.400.075]
        
        rab3 GTP-Binding Proteins [D12.776.157.325.515.400.100]
        
        rab4 GTP-Binding Proteins [D12.776.157.325.515.400.150]
        
        rab5 GTP-Binding Proteins [D12.776.157.325.515.400.200]
        
        rab7 GTP-Binding Proteins [D12.776.157.325.515.400.600]
        
        ral GTP-Binding Proteins [D12.776.157.325.515.450]
        
        ran GTP-Binding Protein [D12.776.157.325.515.462]
        
        rap GTP-Binding Proteins [D12.776.157.325.515.475]
        
        Ras Homolog Enriched in Brain Protein [D12.776.157.325.515.488]
        
        ras Proteins [D12.776.157.325.515.500]
        
        rho GTP-Binding Proteins [D12.776.157.325.515.700]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Intracellular Signaling Peptides and Proteins [D12.776.476]
    - GTP-Binding Proteins [D12.776.476.338]
      - Monomeric GTP-Binding Proteins [D12.776.476.338.400]
        
        ADP-Ribosylation Factors [D12.776.476.338.400.100]
        
        rab GTP-Binding Proteins [D12.776.476.338.400.400]
        
        rab1 GTP-Binding Proteins [D12.776.476.338.400.400.025]
        
        rab2 GTP-Binding Protein [D12.776.476.338.400.400.050]
        
        rab27 GTP-Binding Proteins [D12.776.476.338.400.400.075]
        
        rab3 GTP-Binding Proteins [D12.776.476.338.400.400.100]
        
        rab4 GTP-Binding Proteins [D12.776.476.338.400.400.150]
        
        rab5 GTP-Binding Proteins [D12.776.476.338.400.400.200]
        
        rab7 GTP-Binding Proteins [D12.776.476.338.400.400.600]
        
        ral GTP-Binding Proteins [D12.776.476.338.400.450]
        
        ran GTP-Binding Protein [D12.776.476.338.400.462]
        
        rap GTP-Binding Proteins [D12.776.476.338.400.475]
        
        Ras Homolog Enriched in Brain Protein [D12.776.476.338.400.488]
        
        ras Proteins [D12.776.476.338.400.500]
        
        rho GTP-Binding Proteins [D12.776.476.338.400.700]

rab GTP-Binding Proteins Preferred

Concept UI: M0328226
Scope Note: A large family of MONOMERIC GTP-BINDING PROTEINS that play a key role in cellular secretory and endocytic pathways.
Terms: rab GTP-Binding Proteins Preferred Term
Term UI T358226
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); Rab GTPase
Term UI T000996612
Date11/15/2019
LexicalTag NON
ThesaurusID NLM (2021); rab GTP-Binding Protein
Term UI T000996613
Date11/15/2019
LexicalTag NON
ThesaurusID NLM (2021); rab G-Proteins
Term UI T358965
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); rab GTPases
Term UI T358966
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000)

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