MeSH Browser

MeSH Heading: rac1 GTP-Binding Protein
Tree Number(s): D08.811.277.040.330.300.400.700.100.500; D12.776.157.325.515.700.100.100; D12.776.476.338.400.700.100.500
Unique ID: D020830
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D020830
Scope Note: A rac GTP-binding protein involved in regulating actin filaments at the plasma membrane. It controls the development of filopodia and lamellipodia in cells and thereby influences cellular motility and adhesion. It is also involved in activation of NADPH OXIDASES. This enzyme was formerly listed as EC 3.6.1.47.
Entry Term(s): TC-25 GTP-Binding Protein; rac1 Protein; ras-Related C3 Botulinum Toxin Substrate 1
Registry Numbers: EC 3.6.5.2
Previous Indexing: G-Proteins (1991-1999)
Public MeSH Note: 2000; RAC1 GENE PRODUCT was indexed under G-PROTEINS 1991-1999 & PROTEINS 1989-1990
History Note: 2000; for RAC1 GENE PRODUCT use RAC GTP-BINDING PROTEINS (NM) 1989-1999
Date Established: 2000/01/01
Date of Entry: 1999/11/03
Revision Date: 2021/05/21

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0328243
Registry Numbers: EC 3.6.5.2
Scope Note: A rac GTP-binding protein involved in regulating actin filaments at the plasma membrane. It controls the development of filopodia and lamellipodia in cells and thereby influences cellular motility and adhesion. It is also involved in activation of NADPH OXIDASES. This enzyme was formerly listed as EC 3.6.1.47.
Terms: rac1 GTP-Binding Protein Preferred Term
Term UI T358243
Date10/12/1999
LexicalTag ABX
ThesaurusID NLM (2000); TC-25 GTP-Binding Protein
Term UI T363401
Date10/12/1999
LexicalTag ABX
ThesaurusID NLM (2000); rac1 Protein
Term UI T363402
Date10/12/1999
LexicalTag ABX
ThesaurusID NLM (2000); ras-Related C3 Botulinum Toxin Substrate 1
Term UI T363403
Date10/12/1999
LexicalTag ABX
ThesaurusID NLM (2000)

rac1 GTP-Binding Protein MeSH Descriptor Data 2024