MeSH Browser

MeSH Heading: Tacrolimus Binding Protein 1A
Tree Number(s): D08.811.399.325.500.400.700.500; D12.776.543.750.705.400.700.500; D12.776.827.344.700.500
Unique ID: D022061
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D022061
Scope Note: A 12-KDa tacrolimus binding protein that is found associated with and may modulate the function of calcium release channels. It is a peptidyl-prolyl cis/trans isomerase which is inhibited by both tacrolimus (commonly called FK506) and SIROLIMUS.
Entry Term(s): FK506-Binding Protein 1; FK506-Binding Protein 1A; FKBP-12; FKBP12; Macrophilin-12
Registry Numbers: EC 5.2.1.-
Previous Indexing: Carrier Proteins (1991-1998); DNA-Binding Proteins (1991-1998); Heat-Shock Proteins (1991-1998); Immunophilins (1999-2000)
Public MeSH Note: 2001; FK 506 BINDING PROTEIN (now TACROLIMUS BINDING PROTEINS) was indexed under IMMUNOPHILINS 1999-2000 & under HEAT-SHOCK PROTEINS, DNA-BINDING PROTEINS, & CARRIER PROTEINS 1991-1998
History Note: 2001; use TACROLIMUS BINDING PROTEINS (NM) 1991-2000
Date Established: 2001/01/01
Date of Entry: 2000/06/23
Revision Date: 2023/05/26

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0182872
Registry Numbers: EC 5.2.1.-
Scope Note: A 12-KDa tacrolimus binding protein that is found associated with and may modulate the function of calcium release channels. It is a peptidyl-prolyl cis/trans isomerase which is inhibited by both tacrolimus (commonly called FK506) and SIROLIMUS.
Terms: Tacrolimus Binding Protein 1A Preferred Term
Term UI T406882
Date02/10/2000
LexicalTag NON
ThesaurusID NLM (2001); FKBP-12
Term UI T212877
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2001); FKBP12
Term UI T212880
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2001); Macrophilin-12
Term UI T212899
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2001); FK506-Binding Protein 1A
Term UI T406260
Date02/02/2000
LexicalTag NON
ThesaurusID NLM (2001); FK506-Binding Protein 1
Term UI T406261
Date02/02/2000
LexicalTag NON
ThesaurusID NLM (2001)

Tacrolimus Binding Protein 1A MeSH Descriptor Data 2025