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Tacrolimus Binding Protein 1A MeSH Descriptor Data 2023


MeSH Heading
Tacrolimus Binding Protein 1A
Tree Number(s)
D08.811.399.325.500.400.700.500
D12.776.543.750.705.400.700.500
D12.776.827.275.700.500
Unique ID
D022061
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D022061
Scope Note
A 12-KDa tacrolimus binding protein that is found associated with and may modulate the function of calcium release channels. It is a peptidyl-prolyl cis/trans isomerase which is inhibited by both tacrolimus (commonly called FK506) and SIROLIMUS.
Entry Term(s)
FK506-Binding Protein 1
FK506-Binding Protein 1A
FKBP-12
FKBP12
Macrophilin-12
Registry Number
EC 5.2.1.-
Previous Indexing
Carrier Proteins (1991-1998)
DNA-Binding Proteins (1991-1998)
Heat-Shock Proteins (1991-1998)
Immunophilins (1999-2000)
Public MeSH Note
2001; FK 506 BINDING PROTEIN (now TACROLIMUS BINDING PROTEINS) was indexed under IMMUNOPHILINS 1999-2000 & under HEAT-SHOCK PROTEINS, DNA-BINDING PROTEINS, & CARRIER PROTEINS 1991-1998
History Note
2001; use TACROLIMUS BINDING PROTEINS (NM) 1991-2000
Date Established
2001/01/01
Date of Entry
2000/06/23
Revision Date
2004/08/02
Tacrolimus Binding Protein 1A Preferred
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